Haemophilus Influenzae Pneumonia

Aka: Haemophilus Influenzae Pneumonia, H. Influenzae Pneumonia

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II. Epidemiology

  1. Second most common cause Community Acquired Pneumonia
    1. Pneumococcal Pneumonia is the most common cause
  2. Frequently complicates Chronic Bronchitis

III. Symptoms and Signs

  1. Similar to Pneumococcal Pneumonia

IV. Labs

  1. Gram Stain
    1. Pleomorphic Gram Negative Rods

V. Management: Antibiotic

  1. Beta-Lactamase Negative HaemophilusInfluenzae
    1. Ampicillin IV or Amoxicillin PO
    2. Azithromycin (Zithromax)
    3. Clarithromycin (Biaxin)
    4. Trimethoprim Sulfamethoxazole (Bactrim or Septra)
    5. Doxycycline
  2. Beta-Lactamase Positive HaemophilusInfluenzae
    1. Amoxicillin-clavulanate (Augmentin)
    2. Second Generation Cephalosporin (e.g. Cefuroxime)
    3. Third Generation Cephalosporin (e.g. Cefotaxime)
    4. Azithromycin (Zithromax)
    5. Clarithromycin (Biaxin)
    6. Fluoroquinolone (e.g. Ciprofloxacin)

VI. References

  1. Gilbert (2001) Sanford Antimicrobial, p. 28

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