II. Background
- Peppermint Oil is the extract of a hybrid of wild mint and spearmint (Mentha x piperita)
III. Indications
- 
                          Pain Dominant Irritable Bowel Syndrome (IBS)- Relaxes gastrointestinal Smooth Muscle
- Reduces pain, distention and Flatulence
- Liu (1997) J Gastroenterol 32:765-8 [PubMed]
- Kline (2001) J Pediatr 138:125-8 [PubMed]
 
- Reduction of spasm related to Colonoscopy, Barium Enema
- Non-Ulcer Dyspepsia
- Tension Headaches (Topical 10% Peppermint Oil)
IV. Contraindications
- 
                          General- Contraindications apply to doses listed below
- Tea is unlikely to cause any serious adverse effects
 
- Pregnancy- May cause uterine bleeding
 
- Hiatal Hernia or severe Gastroesophageal Reflux
- Cholecystitis or Cholelithiasis
V. Adverse Effects
- 
                          Gastroesophageal Reflux
                          - Peppermint decreases LES pressure
 
- Perianal burning
- Blurred Vision
- Nausea or Vomiting
VI. Safety
- Unknown safety in pregnancy
- Unknown safety in Lactation
- Longterm data beyond 12 weeks is lacking
VII. Dosing
- Oral enteric coated oil (for gastrointestinal symptoms)- Adult: 200 to 400 mg orally three times daily
- Child: 100 to 200 mg orally three times daily (if over age 8 years)
 
- Topical Peppermint Oil 10%  (for Tension Headache)- Applied to area of Headache
 
VIII. References
- (2024) Presc Lett 31(12): 72
- Kligler (2007) Am Fam Physician 75(7):1027-30 [PubMed]
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Related Studies
| menthol (on 1/18/2023 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| MENTHOL COLD-HOT 5% PATCH | Generic OTC | $0.71 each | 
