MSM

Aka: MSM, Methylsulfonylmethane

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II. Indications

  1. Osteoarthritis

III. Sources

  1. Endogenous: Adrenal Gland
  2. Plant source: Fruits and vegetables

IV. Efficacy: Insufficient evidence to support use

  1. Only short-term (<3 months) efficacy and safety data available
  2. Moderate reduction pain and swelling without an effect on Joint Stiffness

V. Dosing

  1. MSM 500 mg orally three times daily (maximum: 3 grams twice daily)

VI. References

  1. Kim (2006) Osteoarthritis Cartilage 14:286-94 [PubMed]

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Ontology: methylsulfonylmethane (C0058231)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH C025910
SnomedCT 412192002, 412190005
English dimethyl sulfone, Methane, sulfonylbis-, methyl sulfone, methyl sulfonmethane, methylsulfonylmethane (medication), methylsulfonylmethane, Dimethyl Sulphone, Sulfonylbismethane, MSM, Methylsulfonyl Methane, dimethyl sulfone [Chemical/Ingredient], methane methyl sulfonyl, methyl sulfones, methyl sulfonyl methane, DIMETHYL SULFONE, Dimethyl Sulfone, Dimethyl sulfone (product), Dimethyl sulfone (substance), Dimethyl sulfone, Dimethyl sulphone, MSM - Methylsulfonylmethane, Methylsulfonylmethane, METHYLSULFONYLMETHANE
Spanish dimetilsulfona (producto), dimetilsulfona (sustancia), dimetilsulfona
Derived from the NIH UMLS (Unified Medical Language System)

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