Myoinositol

Aka: Myoinositol, Inositol

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II. Physiology

  1. Simple Carbohydrate metabolized to Phosphatidylinositol
  2. Acts as second messenger to stimulate Calcium release
  3. No known deficiency states in humans

III. Indications

  1. Anxiety Disorder
    1. Panic Disorder
    2. Obsessive Compulsive Disorder (possibly)
  2. Other purported benefits
    1. May improve neural function in Diabetes Mellitus

IV. Preparations: Dietary sources (B Vitamin Complex part)

  1. Beans
  2. Citrus fruit
  3. Nuts
  4. Rice
  5. Veal
  6. Pork
  7. Wheat germ

V. Dosing

  1. Panic Disorder: 12-18 grams daily

VI. Efficacy

  1. Effective in Panic Disorder
    1. Benjamin (1995) Am J Psychiatry 152:1084-6 [PubMed]
    2. Palatnik (2001) J Clin Psychopharmacol 21:335-9 [PubMed]
  2. Possibly effective in Obsessive-Compulsive Disorder
    1. Fux (1996) Am J Psychiatry 153:1219-21 [PubMed]

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