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Definition (NCI)
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A phosphatidic acid combined with inositol found in biomembranes and a precursor to certain cellular signals. Sometimes referred to as inositide. It is a very important minor phospholipid in eukaryotes, involved in signal transduction processes. Contains myo inositol linked through the 1 hydroxyl group to phosphatidic acid. The 4 phosphate (PIP) and 4, 5 bisphosphate derivatives PIP2) are formed and broken down in membranes by the action of specific kinases and phosphatases (futile cycles). Signal sensitive phospholipase C enzymes remove the inositol moiety, in particular from 1,4,5 trisphosphate (PIP2) as inositol 1,4,5 triphosphate (Ins P3: IP3). Both the diacyl glycerol and products act as second messengers.(On-line Medical Dictionary)
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Definition (MSH)
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Derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to the hexahydroxy alcohol, myo-inositol. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid, myo-inositol, and 2 moles of fatty acids.
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Definition (CSP)
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derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to the hexahydroxy alcohol, myoinositol.
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| Concepts |
Biologically Active Substance
(T123)
, Lipid
(T119)
|
| MSH |
D010716
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| SnomedCT |
55521004
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| LNC |
LP15799-7, MTHU013138 |
| English |
Inositide Phospholipids, Inositol Phosphoglycerides, Inositol Phospholipids, Phosphoglycerides, Inositol, Phosphoinositides, Phospholipids, Inositide, Phospholipids, Inositol, Phosphatidyl Inositol, Phosphatidylinositol, PtdIns, Inositol, Phosphatidyl, phosphoinositide, PTDIN, inositol phospholipid, Phosphatidylinositols, Phosphatidylinositols [Chemical/Ingredient], phosphatidylinositol, phosphatidyl inositol, PI, Phosphatidyl inositol, Phosphatidyl inositol (substance) |
| Swedish |
Fosfatidylinositoler
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| Czech |
fosfatidylinositoly, fosfoinositidy |
| Finnish |
Fosfatidyyli-inositolit
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| Italian |
Inositolo fosfolipidi, Fosfatidil inositolo, Inositolfosfogliceridi, PtdIns, Fosfatidilinositolo, Inositolfosfolipidi, Fosfoinositidi, Fosfatidilinositoli |
| Russian |
FOSFATIDILINOZITOLY, FOSFOINOZITIDY, INOZITA FOSFOGLITSERIDY, FOSFATIDILINOZITY, ИНОЗИТА ФОСФОГЛИЦЕРИДЫ, ФОСФАТИДИЛИНОЗИТЫ, ФОСФОИНОЗИТИДЫ, ФОСФАТИДИЛИНОЗИТОЛЫ |
| French |
PPI (Phosphoinositides), Phosphatidyl inositol, Phosphoinositides, Phosphatidyl inositols, Monophospho inositide |
| Polish |
Fosfoinozytydy, Fosfatydyloinozytole |
| Japanese |
イノシトールリン脂質, イノシトールホスホグリセリド, ホスファチジルイノシトール, ホスホイノシチド, モノホスホイノシチド, イノシトールホスホリピド, イノシトール燐脂質, ホスファチジルイノシチド |
| Portuguese |
Fosfoglicérides de Inositol, Fosfatidilinositóis, Fosfoglicerídeos de Inositol, Fosfoinositídeos, Ptdinas |
| Spanish |
fosfatidilinositol (sustancia), fosfatidilinositol, Fosfatidilinositoles, Fosfogliceridos de Inositol, Fosfoinositidos, PtdIns |
| German |
Inositol-Phosphoglyceride, Phosphatidyl-Inositole, Phosphoinositide, Ptdlns |
