II. Indications
- Uses with good supporting evidence
- Morning Sickness or Hyperemesis Gravidarum
- Postoperative Nausea or Vomiting
- Uses with variable evidence to support
- Conditions in which Ginger is ineffective (avoid)
III. Dosing
IV. Adverse Effects
- Mild gastrointestinal upset (e.g. Reflux, Eructation or Diarrhea)
- Antiplatelet effects
- May increase bleeding risk (avoid within 2 weeks of surgery)
- Hypoglycemia
V. Safety
- Pregnancy
- Mixed safety results
- If used in pregnancy, then use with caution and limit to first trimester
- Late pregnancy use is associated with bleeding, prematurity and decreased Head Circumference in some studies
- Other studies have shown no increased risk of preterm birth or low birth weight
- Effects
- Ginger affects Testosterone binding
- Ginger affects Thromboxane synthetase activity
- Animal studies showed increased Embryo loss
- References
- Mixed safety results
VI. Drug Interactions
- No major P450 or P-Glycoprotein interactions
-
Warfarin (Coumadin)
- Possible interaction
VII. Efficacy: Ginger appears effective in Morning Sickness
- Effective, safe and well tolerated
- Dose of 250 mg four times daily showed benefit in 70% of cases
VIII. Cost
- Inexpensive (<$20 per month)
IX. References
- (2024) Presc Lett 31(3): 18
- White (2007) Am Fam Physician 75:1689-91 [PubMed]
Images: Related links to external sites (from Bing)
Related Studies
| Definition (NCI) | An extract of the rhizome of the perennial plant Zingiber officinale with potential antineoplastic activity. Ginger extract contains a number of different phenolic compounds, some of which have displayed antineoplastic, anti-inflammatory, and antioxidant activities. This agent also exhibits antiemetic properties. |
| Definition (PDQ) | A rhizome herb isolated from the plant Zingiber officinale with potential antineoplastic activity. Ginger contains a number of different phenolic compounds, some of which have displayed antineoplastic, anti-inflammatory, and antioxidant activities. This agent also exhibits antiemetic properties. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=38711&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=38711&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2691" NCI Thesaurus) |
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| English | Ginger Extract, ginger (medication), gingers, ginger extract, extract ginger, ginger, Ginger, Ginger extract, GINGER |
