II. Current uses
- Premenstrual Syndrome
- Irregular Menses
- Infertility
- Menopause
III. Contraindications
- Anticoagulant medication
- Bleeding Diathesis (natural coumarins)
IV. Efficacy
V. Adverse Effects
- Psoralen effects
- Photosensitization
- Dermatitis
- Coumarin-like derivatives
- May increase bleeding risk
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| Definition (MSH) | A plant species of the family APIACEAE that is the source of dong quai. |
| Concepts | Plant (T002) |
| MSH | D029971 |
| Swedish | Angelica sinensis |
| Czech | Angelica sinensis, děhel čínský |
| Finnish | Angelica sinensis |
| Spanish | Angelica sinensis |
| French | Angélique chinoise, Angelica sinensis, Dang Gui, Dang Qui, Dong Quai, Tang Kuei |
| English | Angelica sinenses, sinenses, Angelica, sinensis, Angelica, dong quai, angelica sinensis, Angelica sinensis, Chinese angelica, dong gui, Angelica sinensis (Oliv.) Diels |
| Polish | Angelica sinensis |
| Korean | 당귀 |
| Norwegian | Dong quai, Kinesisk kvann, Angelica sinensis |
| German | Angelica sinensis |
| Italian | Angelica sinensis |
| Russian | ANGELICA SINENSIS |
| Dutch | Angelica sinensis |
| Portuguese | Angelica sinensis |
Ontology: Angelica sinensis preparation (C1122975)
| Definition (PDQ) | An herbal extract derived from the root of the plant Angelica sinensis with possible antiinflammatory, antispasmodic, vasodilatory, estrogenic, and antitumor activities. Angelica sinensis contains volatile oils, including safrole, isosafrole, and n-butylphthalide; coumarin derivatives, including psoralens, bergapten, osthol, imperatorin, and oxypeucedanin; and ferulic acid. The coumarin derivatives in this agent may vasodilate and relax smooth muscle and may exhibit additive anticoagulant effects. Ferulic acid, a phenolic phytochemical present in plant cell walls, may neutralize free radicals such as reactive oxygen species.In addition, Angelica sinensis extract has been shown to inhibit the growth and induce apoptosis of glioblastoma mutltiforme brain tumor cells through p53-dependent and p53-independent pathways. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=467927&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=467927&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C60817" NCI Thesaurus) |
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | C109695 |
| SnomedCT | 412176007 |
| English | Dong Quai Extract, Dong Quai Root Extract, Dong Quai Root, Dong Quai, dong quai, dong quai (medication), dong quai [Chemical/Ingredient], dong quai root, Angelica sinensis preparation, Angelica sinensis extract (substance), Angelica sinensis extract, Dong quai extract, DONG QUAI |
| Spanish | extracto de Angelica sinensis (sustancia), extracto de Angelica sinensis |
