Blue Cohosh

Aka: Blue Cohosh, Caulophyllum thalictroides

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II. Current use

  1. Oxytocin-like agent used in Labor Augmentation

III. Contraindications

  1. Hypertension
  2. Underlying Cardiovascular disease

IV. Mechanism

  1. Perennial plant growing in North America
    1. Member of Berberidaceae family
  2. Active ingredients
    1. Glycoside: Caulosaponin
    2. Alkaloid: Methylcysteine (nicotine-like compound)
      1. Increases Blood Pressure
      2. Stimulates uterine contractions
      3. Stimulates gastrointestinal motility
      4. Stimulates coronary Vasoconstriction

V. Efficacy

  1. No studies supporting efficacy or safety

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Related Studies

Ontology: Caulophyllum thalictroides (C0330273)

Definition (MSH) Caulophyllum thalictroides (L.) Michx.
Concepts Plant (T002)
MSH D028145
SnomedCT 52504004
English Caulophyllum thalictroides, thalictroide, Caulophyllum, thalictroides, Caulophyllum, Caulophyllum thalictroide, Blue Cohoshs, Cohoshs, Blue, blue cohosh, Blue Cohosh, Cohosh, Blue, papooseroot, Blue cohosh, Caulophyllum thalictroides (organism)
German Blauer Cohosh, Cohosh, blauer
French Caulophyllum thalictroides, Cohosh bleu
Italian Caulophyllum thalictroides
Norwegian Caulophyllum thalictroides
Portuguese Raiz Papilha, Raiz Indígena
Spanish Caulophyllum thalictroides (organismo), Caulophyllum thalictroides, Cohosh Azul
Dutch Blue cohosh, Cohosh, blue
Derived from the NIH UMLS (Unified Medical Language System)

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