II. Background
- Protein (120 Amino Acid) found in all human cells with a nucleus, as well as nearly all body fluids and tissues
III. Indications
- Alternative to Serum Creatinine as a measure of GFR
- Consider when estimated GFR is decreased, with suspected False Positive test
- Abnormal GFR measurement with no known structural Kidney disease, CKD risk factors or albuminuria
IV. Contraindications (inaccurate Serum Cystatin-C)
- Acute Kidney Injury
- Inflammatory states
- Thyroid dysfunction
V. Disadvantages
- May not be available at all facilities
VI. Resources
- National Kidney Foundation GFR Calculator
- Wikipedia