II. Indications
III. Precautions
- Results altered by Hyperkalemia Management
- Obtain lab sample prior to intervention if possible
- Do not delay treatment in emergent Hyperkalemia
IV. Labs
- Serum Potassium and Serum Osmolality
- Spot urine for Urine Potassium and Urine Osmolality
V. Calculation: Transtubular Potassium Gradient (TTPG)
VI. Interpretation: Fractional Excretion of Potassium
- TTPG <6-8%: Renal cause of Hyperkalemia
- Hypoaldeosteronism suggested by very low TTPG
- TTPG >6-8: Extrarenal cause of Hyperkalemia
- May also be increased in Chronic Renal Failure
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Related Studies
| Concepts | Laboratory Procedure (T059) |
| Italian | Gradiente transtubulare di potassio |
| Japanese | 経尿細管性カリウム勾配, ｹｲﾆｮｳｻｲｶﾝｾｲｶﾘｳﾑｺｳﾊﾞｲ |
| English | Transtubular potassium gradient |
| Czech | Transtubulární draslíkový gradient |
| Hungarian | Transtubularis kálium gradiens |
| Portuguese | Gradiente transtubular de potássio |
| Spanish | Gradiente transtubular de potasio |
| Dutch | transtubulaire kaliumgradiënt |
| French | Gradient trans-tubulaire du potassium |
| German | Transtubulaerer Kaliumgradient |
