II. Physiology
- Uric Acid is a metabolic-by-product of Purine catabolism
- Uricase converts Uric Acid to allantoin in most mammals, but is dysfunctional in humans
- Uric Acid varies considerably with Purine and Alcohol intake, as well as Renal Function
III. Interpretation: Normal
- Uric Acid: 2-7 mg/dl
IV. Interpretation: Increased (Hyperuricemia)
- See Hyperuricemia
V. Interpretation: Decreased
- Medications
- Allopurinol
- High dose ASA
- Probenecid
- Coumadin
- Corticosteroids
- SIADH
- Renal tubule disease (Fanconi Syndrome)
- Liver disease
- Alcohol
- Wilson's Disease
- Hemochromatosis
- Protein or Purine deficient diet
- Xanthine-oxidase deficiency