Serum Calcium

Aka: Serum Calcium, Corrected Serum Calcium, Ionized Calcium, Free Calcium

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II. Physiology

  1. See Calcium Homeostasis

III. Interpretation: Normal (normal range varies by individual labs)

  1. Serum Calcium: 8 to 10 mg/dl
  2. Ionized (free) Calcium: 4 to 5.6 mg/dl

IV. Interpretation: Correcting Serum Calcium for Albumin

  1. No correction needed for Ionized Calcium
  2. Calculation
    1. Calcium + ((Normal Albumin - Serum Albumin) x 0.8)
    2. Where normal albumin is often 4.0

V. Interpretation: Abnormal

  1. Hypercalcemia
    1. Mild: Serum Calcium 10.5 to 12 mg/dl
    2. Moderate: Serum Calcium 12 to 14 mg/dl
    3. Critical: Serum Calcium 14 mg/dl or higher
  2. Hypocalcemia
    1. Serum Calcium under 8.0 mg/dl

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