II. Pathophysiology

  1. Hypercalcemia from excess ingestion alkali and Calcium
    1. Excessive Milk or Calcium supplements
    2. Excessive soluble alkali (absorbable Antacid)
      1. Sodium Bicarbonate
      2. Calcium Carbonate
    3. Potentiated by Vitamin D supplementation
  2. Chronic milk-alkali leads to Renal Insufficiency
    1. Soft tissue calcification of Kidneys
    2. Nephrocalcinosis

III. Signs

IV. Labs

  1. Renal Function
    1. Mildly elevated Blood Urea Nitrogen (BUN)
  2. Electrolytes
    1. Serum Calcium elevated
    2. Serum Phosphorus slightly elevated
  3. Arterial Blood Gas (ABG)
    1. Mild alkalosis

V. Management

  1. Rehydration
  2. Discontinue Calcium supplements
  3. Discontinue alkali (Antacids)

VI. Complications

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Related Studies

Ontology: Milk-Alkali Syndrome (C0026141)

Concepts Disease or Syndrome (T047)
MSH D006934
SnomedCT 43258006
English Milk Alkali Syndrome, Syndrome, Milk-Alkali, MILK-ALKALI SYNDROME, milk alkali syndrome (diagnosis), milk alkali syndrome, drinkers milk syndrome, burnett's syndrome, burnett syndrome, Burnett syndrome, Burnett's syndrome, Milk-alkali syndrome, Milk alkali syndrome, Milk alkali syndrome (disorder), Burnett, milk-alkali syndrome, milk-alkali; syndrome, syndrome; milk-alkali, Milk-Alkali Syndrome
Italian Sindrome da latte e alcali, Sindrome di Burnett, Sindrome latte-alcali
Dutch syndroom van Burnett, melk-alkali; syndroom, syndroom; melk-alkali, melk-alkali syndroom, Melk-alkalisyndroom
German Burnett-Syndrom, Milch-Alkali-Syndrom, MILCHALKALISYNDROM, Milchalkalisyndrom
Portuguese Síndrome de Burnett, Síndrome do Leite-Antiácido, SINDROME DE BURNETT, Síndrome lácteo-alcalina
Spanish Síndrome de Burnett, Síndrome de Leche-Alcalinos, SINDROME LECHE-ALCALINOS, síndrome de Burnett, síndrome de leche alcalina, síndrome lactoalcalino (trastorno), síndrome lactoalcalino, Síndrome de leche y alcalinos
Japanese バーネット症候群, ミルク・アルカリ症候群, ミルクアルカリショウコウグン, バーネットショウコウグン
French Syndrome de Burnett, SYNDROME DE BURNETT, Syndrome des buveurs de lait et d'alcalins, Syndrome du lait et des alcalins
Czech Milk-alkali syndrom, Burnettův syndrom, milk-alkali syndrom
Hungarian Tej-alkalia syndroma, Burnett-syndroma
Norwegian Melk-alkali syndrom