II. Associated Conditions

  1. Familial Primary Hyperparathyroidism (occurs in >80% of MEN I cases)
  2. Pituitary Adenoma
  3. Pancreatic islet tumors
  4. Zollinger-Ellison Syndrome
    1. Hypergastrinemia
    2. Peptic Ulcer Disease

III. Prevention: Family Members of MEN I patients

  1. Consider annual lab screening starting at age 8 years
    1. Serum Calcium annually
    2. Consider PTH Level annually or if Serum Calcium is abnormal
    3. Malone (2004) Otolaryngol Clin North Am 37(4): 715-36 [PubMed]

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