II. Precautions
- Write for generic Nifedipine ER to allow pharmacist to substitute between multiple similar ER preparations
- (2016) Presc Lett 23(7): 39-40
III. Pharmacology
- Prototype for Dihydropyridine Calcium Channel Blockers
IV. Indications
V. Contraindications
- Congestive Heart Failure
- Aortic Stenosis
- Avoid in Diabetes Mellitus (may increase Proteinuria)
- Concomitant use of Magnesium Sulfate
- Theoretically deactivates Calcium Gluconate antidote
VI. Dosing: Hypertension
- Nifedipine (Procardia) XL 30-60 mg PO qd (Maximum 120 qd)
VII. Dosing: Preterm Labor
- Load: Nifedipine 10 mg sublingual every 20 minutes for 3 doses
- Maintenance: Nifedipine10 to 20 mg PO every 4 to 8 hours
VIII. Adverse Effects
- See Calcium Channel Blockers
- Avoid short acting agents (increased coronary risk)
- Fetal effects
- Risk of Intrauterine Growth Retardation
IX. Monitoring: When used in Preterm Labor
- Blood Pressure
- Edema
- Serial Fetal Ultrasounds
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Related Studies
| nifedipine (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| NIFEDIPINE 10 MG CAPSULE | Generic | $0.32 each |
| NIFEDIPINE 20 MG CAPSULE | Generic | $0.97 each |
| NIFEDIPINE ER 30 MG TABLET | Generic | $0.13 each |
| NIFEDIPINE ER 60 MG TABLET | Generic | $0.15 each |
| NIFEDIPINE ER 90 MG TABLET | Generic | $0.28 each |