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Ontology:
Brevibloc
(C0591189)
| Concepts |
Pharmacologic Substance
(T121)
, Organic Chemical
(T109)
|
| MSH |
C036604
|
| English |
Brevibloc, Baxter brand of esmolol hydrochloride, Boots brand of esmolol hydrochloride, Prasfarma brand of esmolol hydrochloride, Rhône-Poulenc Rorer brand of esmolol hydrochloride |
Ontology:
Esmolol hydrochloride
(C0700606)
|
Definition (NCI)
|
The hydrochloride salt form of esmolol, a short and rapid-acting beta adrenergic antagonist belonging to the class II anti-arrhythmic drugs and devoid of intrinsic sympathomimetic activity. Esmolol hydrochloride competitively blocks beta-1 adrenergic receptors in cardiac muscle and reduces the contractility and cardiac rate of heart muscle, thereby decreasing cardiac output and myocardial oxygen demands. This agent also decreases sympathetic output centrally and blocks renin secretion. At higher doses, esmolol hydrochloride also blocks beta-2 receptors located in bronchial and vascular smooth muscle, thereby leading to smooth muscle relaxation.
|
| Concepts |
Pharmacologic Substance
(T121)
, Organic Chemical
(T109)
|
| MSH |
C036604
|
| SnomedCT |
35318005, 318624002 |
| English |
4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoic Acid Methyl Ester HCl, (+-)-Methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate Hydrochloride, Esmolol Hydrochloride, esmolol hydrochloride (medication), ESMOLOL HYDROCHLORIDE, esmolol HCl, Esmolol hydrochloride, Esmolol hydrochloride product, Esmolol hydrochloride (substance), Esmolol hydrochloride product (product), Esmolol hydrochloride product (substance), esmolol hydrochloride |
| Spanish |
producto con clorhidrato de esmolol (producto), clorhidrato de esmolol (producto), producto con clorhidrato de esmolol, clorhidrato de esmolol (sustancia), clorhidrato de esmolol, producto (producto), clorhidrato de esmolol, producto, clorhidrato de esmolol |
