II. Beta Receptor Effects
- Beta Receptor General Effects
- Eye
- Relaxes Ciliary Muscle (resulting in taut zonule fibers, flatter lens with less focusing power)
- Eye
- Beta 1 Receptor
- Myocardium
- Increases Myocardial Contractility
- Increases Heart Rate
- Accelerates Sinoatrial Node
- Accelerates ectopic Pacemakers
- Metabolic
- Myocardium
- Beta 2 Receptor
- Vessel
- Vasodilatation
- Lung
- Bronchodilation
- Genitourinary and Gastrointestinal
- Metabolic
- Liver Gluconeogenesis and glycogenolysis
- Vessel
III. Medications: Beta Adrenergics
- Beta Adrenergic Agonist (Beta Adrenergic Receptor)
- Beta Non-Specific
- Beta 1 Selective
- Norepinephrine
- Dobutamine
- Prenalterol
- Beta 2 Selective (See Bronchodilator)
- Fenoterol
- Albuterol
- Terbutaline
- Metaproterenol
-
Beta Adrenergic Antagonist
- Beta Non-specific
- Beta 1 Selective
- Metoprolol
- Acebutolol
- Alprenolol
- Atenolol
- Esmolol
- Beta 2 Selective
- Butoxamine
Images: Related links to external sites (from Bing)
Related Studies
| Definition (MSH) | A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). The adrenergic beta-1 receptors are equally sensitive to EPINEPHRINE and NOREPINEPHRINE and bind the agonist DOBUTAMINE and the antagonist METOPROLOL with high affinity. They are found in the HEART, juxtaglomerular cells, and in the central and peripheral nervous systems. |
| Definition (NCI) | Beta 1 adrenergic receptor protein (477 aa, 51 kD) is a cell communication process protein that is encoded by the human ADRB1 gene and has a role in signal transduction. |
| Concepts | Receptor (T192) , Amino Acid, Peptide, or Protein (T116) |
| MSH | D018342 |
| SnomedCT | 45585002 |
| English | beta-1 Adrenergic Receptors, Adrenergic Receptor, beta-1, Adrenergic Receptors, beta-1, beta 1 Adrenergic Receptors, beta-1 Adrenergic Receptor, Receptor, beta-1 Adrenergic, Receptors, beta-1 Adrenergic, Receptor, Adrenergic, beta-1, beta 1 Adrenergic Receptor, Adrenergic beta-1 Receptors, Adrenergic Receptor, beta 1, Receptors, Adrenergic beta-1, Receptors, beta 1 Adrenergic, beta-1 Receptors, Adrenergic, RECEPT ADREN BETA 1, RECEPT BETA 1 ADREN, RECEPTORS BETA 001 ADRENERGIC, ADRENERGIC RECEPTORS BETA 01, BETA 1 ADREN RECEPT, BETA ADRENERGIC RECEPTORS 01, ADREN BETA 1 RECEPT, beta-1 Adrenergic receptor site, Beta 1 Adrenergic Receptor, Receptors, Adrenergic, beta-1 [Chemical/Ingredient], Adrenergic beta 1 Receptors, beta-1 Adrenergic receptor (substance), beta-1 Adrenergic receptor, Beta 1 Receptor, Beta-1 Adrenoceptor, Beta-1 Adrenoreceptor, ADRB1, Receptors, Adrenergic, beta-1 |
| Swedish | beta-1-adrenerga receptorer |
| Finnish | Beeta-1-adrenergiset reseptorit |
| Russian | ADRENERGICHESKIE BETA-1 RETSEPTORY, RETSEPTORY BETA-1 ADRENERGICHESKIE, RETSEPTORY ADRENERGICHESKIE BETA-1, BETA-1 ADRENERGICHESKIE RETSEPTORY, АДРЕНЕРГИЧЕСКИЕ БЕТА-1 РЕЦЕПТОРЫ, БЕТА-1 АДРЕНЕРГИЧЕСКИЕ РЕЦЕПТОРЫ, РЕЦЕПТОРЫ АДРЕНЕРГИЧЕСКИЕ БЕТА-1, РЕЦЕПТОРЫ БЕТА-1 АДРЕНЕРГИЧЕСКИЕ |
| Italian | Recettore beta-1 adrenergico, Recettori beta-1 adrenergici |
| German | ADRENERGE REZEPTOREN BETA 01, REZEPTOREN BETA 001 ADRENERGE, BETA ADRENERGE REZEPTOREN 01, Adrenerge Beta-1-Rezeptoren, Beta-1-adrenerge Rezeptoren, Rezeptoren, Beta-1-adrenerge, Rezeptoren, adrenerge, Beta-1- |
| French | Récepteur bêta-1 adrénergique, Récepteurs bêta-1 adrénergiques |
| Czech | beta-1-adrenoreceptory, receptory adrenergní beta-1, beta-1-adrenergní receptory |
| Spanish | Receptores Adrenérgicos beta-1, Receptores Adrenérgicos beta 1, receptor beta - 1 adrenérgico (sustancia), receptor beta - 1 adrenérgico, Receptores beta-1 Adrenérgicos |
| Portuguese | Receptores Adrenérgicos beta-1, Receptores beta-1 Adrenérgicos, Receptores Adrenérgicos beta 1 |
| Polish | Receptory adrenergiczne beta 1 |
| Japanese | β1受容体, アドレナリンベータ1受容体, アドレナリンβ1受容体, ベータ1アドレナリンレセプター, ベータ1アドレナリン受容体, 受容体-アドレナリン作用性ベータ1, アドレナリン作用性ベータ1受容体, ベータ1受容体, 受容体-アドレナリンβ1 |
Ontology: beta-2 Adrenergic Receptors (C0001643)
| Definition (MSH) | A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). The adrenergic beta-2 receptors are more sensitive to EPINEPHRINE than to NOREPINEPHRINE and have a high affinity for the agonist TERBUTALINE. They are widespread, with clinically important roles in SKELETAL MUSCLE; LIVER; and vascular, bronchial, gastrointestinal, and genitourinary SMOOTH MUSCLE. |
| Definition (NCI) | Beta 2 adrenergic receptor (413 aa, 47 kD) is a cell communication protein that is encoded by the human ADRB2 gene and has roles in endosome to lysosome transport and signal transduction. |
| Concepts | Receptor (T192) , Amino Acid, Peptide, or Protein (T116) |
| MSH | D018343 |
| SnomedCT | 90971001 |
| English | Adrenergic Receptor, beta-2, Adrenergic Receptors, beta-2, beta 2 Adrenergic Receptors, beta-2 Adrenergic Receptor, Receptor, beta-2 Adrenergic, Receptors, beta-2 Adrenergic, Receptor, Adrenergic, beta-2, Adrenergic beta-2 Receptors, Receptors, Adrenergic, beta-2, Adrenergic Receptor, beta 2, Receptors, Adrenergic beta-2, Receptors, beta 2 Adrenergic, beta-2 Receptors, Adrenergic, RECEPTORS BETA 002 ADRENERGIC, ADRENERGIC RECEPTORS BETA 02, RECEPTORS ADRENERGIC BETA 2, BETA 2 ADREN RECEPT, RECEPT ADREN BETA 2, BETA ADRENERGIC RECEPTORS 02, RECEPT BETA 2 ADREN, ADREN BETA 2 RECEPT, beta-2 Adrenergic receptor site, Receptors, Adrenergic, beta-2 [Chemical/Ingredient], 2 adrenergic beta receptors, beta 2 adrenergic receptors, Adrenergic beta 2 Receptors, beta-2 Adrenergic receptor (substance), beta-2 Adrenergic receptor, beta-2 Adrenergic Receptors, Catecholamine Receptor, BAR, Adrenergic, Beta-2-, Receptor, Surface, ADRB2R, ADRB2, ADRBR, B2AR, Beta-2 Adrenergic Receptor, Beta-2 Adrenoceptor, Beta-2-Adrenergic Receptor, Beta-Adrenergic Receptor |
| Swedish | beta-2-adrenerga receptorer |
| Finnish | Beeta-2-adrenergiset reseptorit |
| Russian | ADRENERGICHESKIE BETA-2 RETSEPTORY, RETSEPTORY ADRENERGICHESKIE BETA-2, BETA-2 ADRENERGICHESKIE RETSEPTORY, RETSEPTORY BETA-2 ADRENERGICHESKIE, АДРЕНЕРГИЧЕСКИЕ БЕТА-2 РЕЦЕПТОРЫ, БЕТА-2 АДРЕНЕРГИЧЕСКИЕ РЕЦЕПТОРЫ, РЕЦЕПТОРЫ АДРЕНЕРГИЧЕСКИЕ БЕТА-2, РЕЦЕПТОРЫ БЕТА-2 АДРЕНЕРГИЧЕСКИЕ |
| Italian | Recettore beta-2 adrenergico, Recettori beta-2 adrenergici |
| German | REZEPTOREN ADRENERGE BETA 2, ADRENERGE REZEPTOREN BETA 02, BETA ADRENERGE REZEPTOREN 02, REZEPTOREN BETA 002 ADRENERGE, Adrenerge Beta-2-Rezeptoren, Beta-2-adrenerge Rezeptoren, Rezeptoren, Beta-2-adrenerge, Rezeptoren, adrenerge, Beta-2- |
| French | Récepteurs bêta-2 adrénergiques, Récepteur bêta-2 adrénergique |
| Czech | beta-2-adrenergní receptory, receptory adrenergní beta-2, beta-2-adrenoreceptory |
| Spanish | Receptores Adrenérgicos beta-2, Receptores Adrenérgicos beta 2, receptor beta - 2 adrenérgico (sustancia), receptor beta - 2 adrenérgico, Receptores beta-2 Adrenérgicos |
| Portuguese | Receptores Adrenérgicos beta-2, Receptores Adrenérgicos beta 2, Receptores beta-2 Adrenérgicos |
| Polish | Receptory adrenergiczne beta 2 |
| Japanese | アドレナリンベータ2受容体, β2受容体, アドレナリンβ2受容体, ベータ2アドレナリンレセプタ, ベータ2アドレナリン受容体, 受容体-アドレナリン作用性ベータ2, アドレナリン作用性ベータ2受容体, ベータ2受容体, 受容体-アドレナリンβ2 |
Ontology: Adrenergic beta-Agonists (C0001644)
| Definition (MSH) | Drugs that selectively bind to and activate beta-adrenergic receptors. |
| Concepts | Pharmacologic Substance (T121) |
| MSH | D000318 |
| SnomedCT | 349920008, 373227004 |
| English | beta Adrenergic Receptor Agonists, Adrenergic beta Agonist, Adrenergic beta Agonists, Adrenergic beta Receptor Agonist, Adrenergic beta Receptor Agonists, Adrenergic beta-Agonist, Adrenergic beta-Receptor Agonist, Adrenergic beta-Receptor Agonists, Agonist, Adrenergic beta-Receptor, Agonist, beta-Adrenergic, Agonist, beta-Adrenergic Receptor, Agonists, Adrenergic beta-Receptor, Agonists, beta-Adrenergic, Agonists, beta-Adrenergic Receptor, Receptor Agonist, beta-Adrenergic, Receptor Agonists, beta Adrenergic, Receptor Agonists, beta-Adrenergic, Receptors Agonists, Adrenergic beta, beta Adrenergic Agonist, beta Adrenergic Agonists, beta Adrenergic Receptor Agonist, beta-Adrenergic Agonist, beta-Adrenergic Receptor Agonist, beta-Adrenergic Receptor Agonists, beta-Agonist, Adrenergic, beta-Agonists, Adrenergic, beta-Receptor Agonist, Adrenergic, beta-Receptor Agonists, Adrenergic, Beta-Adrenergic Agonist, ADREN BETA AG, ADREN BETA RECEPT AGON, BETA ADREN AG, BETA ADREN AGON, ADREN BETA RECEPT AG, RECEPT AGON BETA ADREN, RECEPT AGON ADREN BETA, BETA ADREN RECEPT AG, ADRENERGIC RECEPTOR AGONISTS BETA, ADRENERGIC AGONISTS BETA, ADREN BETA AGON, BETA ADREN RECEPT AGON, beta-Adrenergic Agonists, Betamimetics, antiadrenergic beta receptor agents (medication), antiadrenergic beta receptor agents, adrenergic beta receptor agonists, Adrenergic beta-Agonists, beta-adrenergic receptor agonists, beta adrenergic agonist, beta-adrenergic agonist, beta-adrenergic agonists, agonists beta adrenergic receptor, beta adrenergic agonists, Adrenergic beta agonists, Beta-adrenoceptor agonist, Beta-adrenoceptor agonist (product), Beta-adrenoceptor agonist (substance), Beta-adrenergic Agonists |
| Swedish | Adrenerga betastimulerare |
| Czech | receptory adrenergní beta - agonisté |
| Portuguese | Agonistas beta-Adrenérgicos, Agonistas dos Receptores Adrenérgicos beta, Agonistas Adrenérgicos beta, beta-Agonistas Adrenérgicos, Agonistas dos Receptores beta-Adrenérgicos, Agonistas dos beta-Receptores Adrenérgicos |
| Finnish | Beeta-agonistit |
| French | Agonistes beta-adrénergiques, Agonistes des adrénorécepteurs bêta, Bêta-adrénergiques, Bêta-stimulants, Sympathomimétiques bêta, Agoniste bêta-adrénergique, Agonistes bêta-adrénergiques, Agonistes des récepteurs bêta-adrénergiques, Bêta-mimétiques |
| Russian | ADRENERGICHESKIE BETA-AGONISTY, ADRENORETSEPTOROV-BETA AGONISTY, BETA-ADRENORETSEPTOROV AGONISTY, ADRENERGICHESKIKH BETA-RETSEPTOROV AGONISTY, АДРЕНЕРГИЧЕСКИЕ БЕТА-АГОНИСТЫ, АДРЕНЕРГИЧЕСКИХ БЕТА-РЕЦЕПТОРОВ АГОНИСТЫ, АДРЕНОРЕЦЕПТОРОВ-БЕТА АГОНИСТЫ, БЕТА-АДРЕНОРЕЦЕПТОРОВ АГОНИСТЫ |
| Spanish | Agonistas beta-Adrenérgicos, Agonistas de los beta-Receptores Adrenérgicos, Agonistas Adrenérgicos beta, Agonistas de los Receptores Adrenérgicos beta, Agonistas de los Receptores beta-Adrenérgicos, beta-Agonistas Adrenérgicos, agonista beta adrenérgico (producto), agonista beta adrenérgico (sustancia), agonista beta adrenérgico, agonista betadrenérgico (sustancia), agonista betadrenérgico |
| German | ADRENERGE AGONISTEN BETA, Adrenerge Beta-Agonisten, Beta-Adrenomimetika, Beta-Rezeptorenagonisten |
| Polish | Agoniści adrenergiczni beta, Beta-mimetyki, Agoniści receptora adrenergicznego beta |
| Japanese | β-アドレナリン作動性受容体作用薬, β-作動剤, β-作動薬, β-作用薬, β-刺激薬, β-受容体作用薬, アドレナリンベータアゴニスト, アドレナリン作用性ベータ受容体作用薬, ベータアドレナリン作用性受容体作用薬, β作動薬, β刺激剤, β刺激薬, β受容体刺激薬, アドレナリン作用性ベータ受容体作用剤, アドレナリン作用性ベータ受容体作用物質, アドレナリン作用性ベータ受容器作用物質 |
| Italian | Beta-agonisti adrenergici |
Ontology: beta-adrenergic receptor (C0034785)
| Definition (MSH) | One of two major pharmacologically defined classes of adrenergic receptors. The beta adrenergic receptors play an important role in regulating CARDIAC MUSCLE contraction, SMOOTH MUSCLE relaxation, and GLYCOGENOLYSIS. |
| Definition (NCI) | Expressed by Beta Adrenergic Receptor Genes in effector tissues innervated by postganglionic sympathetic adrenergic fibers, Beta Adrenergic Receptors are one of two major classes of adrenergic receptors (alpha and beta) based on their reactions to norepinephrine and epinephrine, on cellular effects of receptor activation, and on relative affinities and reactions to synthetic blocking or stimulating agents. Beta-adrenergic receptors respond to blocking agents such as propranolol and to activating agents such as isoproterenol. Beta-1 type receptors mediate lipolysis and increase cardiac rate and force of contraction; beta-2 type receptor activation promotes bronchial and vascular smooth muscle relaxation. When coupled to adenylate cyclase through Gs protein, Beta Adrenergic Receptor stimulation results in increased intracellular cyclic AMP. (NCI) |
| Definition (CSP) | coupled through the G protein Gs to adenylate cyclase such that extracellular stimulation results in increased intracellular cyclic AMP; beta-1 mediates lipolysis and cardiostimulation, beta-2 broncho- and vaso- dilation. |
| Concepts | Receptor (T192) , Amino Acid, Peptide, or Protein (T116) |
| MSH | D011943 |
| SnomedCT | 85205004 |
| English | Adrenergic beta Receptors, beta adrenergic receptor, beta Adrenergic Receptors, Receptors, Adrenergic, beta, Receptors, beta Adrenergic, Receptor, Adrenergic, beta, Adrenergic beta-Receptors, Receptors, beta-Adrenergic, beta-Adrenergic Receptors, beta-Receptors, Adrenergic, ADRENERGIC RECEPTORS BETA, RECEPT BETA ADREN, RECEPT ADREN BETA, BETA ADREN RECEPT, ADREN BETA RECEPT, beta-Adrenergic receptor site, Beta adrenergic receptor, Receptors, Adrenergic, beta [Chemical/Ingredient], beta-adrenergic receptor, beta adrenergic receptors, adrenergic beta receptors, beta-adrenergic receptors, Beta adrenoceptors, beta-Adrenergic receptor (substance), beta-Adrenergic receptor, Beta Adrenergic Receptor |
| Swedish | beta-adrenerga receptorer |
| Finnish | Beeta-adrenergiset reseptorit |
| Russian | BETA-ADRENORETSEPTORY, RETSEPTORY BETA-ADRENERGICHESKIE, ADRENERGICHESKIE BETA-RETSEPTORY, BETA-ADRENERGICHESKIE RETSEPTORY, RETSEPTORY ADRENERGICHESKIE BETA, АДРЕНЕРГИЧЕСКИЕ БЕТА-РЕЦЕПТОРЫ, БЕТА-АДРЕНЕРГИЧЕСКИЕ РЕЦЕПТОРЫ, БЕТА-АДРЕНОРЕЦЕПТОРЫ, РЕЦЕПТОРЫ АДРЕНЕРГИЧЕСКИЕ БЕТА, РЕЦЕПТОРЫ БЕТА-АДРЕНЕРГИЧЕСКИЕ |
| Italian | Recettore beta adrenergico, Recettori beta adrenergici |
| German | ADRENERGE REZEPTOREN BETA, Adrenerge Beta-Rezeptoren, Beta-adrenerge Rezeptoren, Rezeptoren, Beta-adrenerge, Rezeptoren, adrenerge, Beta- |
| Croatian | RECEPTORI, ADRENERGIČKI, BETA |
| French | Récepteurs bêta-adrénergiques |
| Czech | beta-adrenergní receptory, receptory adrenergní beta, beta-adrenoreceptory |
| Polish | Receptory adrenergiczne beta |
| Japanese | アドレナリンベータ受容体, アドレナリン作用性ベータ受容体, βレセプター, β受容体, アドレナリンβ受容体, ベータアドレナリンレセプター, ベータアドレナリン受容体, ベータ受容体, 受容体-アドレナリン作用性ベータ, 受容体-アドレナリンβ |
| Portuguese | Receptores beta Adrenérgicos, Receptores beta-Adrenérgicos, Receptores Adrenérgicos beta |
| Spanish | Receptores beta-Adrenérgicos, Receptores Adrenérgicos beta, Receptores beta Adrenérgicos, receptor beta - adrenérgico (sustancia), receptor beta - adrenérgico |
