Tamsulosin

Aka: Tamsulosin, Flomax

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II. Indications

  1. Benign Prostatic Hypertrophy
  2. Medical Expulsive Therapy for Ureteral Stone (Ureterolithiasis)

III. Dosing

  1. Start 0.4 mg orally daily
  2. Maximum 0.8 mg/day

IV. Adverse Effects

  1. See Selective Alpha-1a Antagonist
  2. Rare Sulfa Allergy cross-reactivity
  3. Postural Hypotension (esp. when combined with Antihypertensives)
  4. Floppy Iris Syndrome
  5. Ejaculatory Dysfunction (class effect)

V. Drug Interactions

  1. Avoid all Selective Alpha-1a Antagonists with strong CYP3A4 inhibitors (e.g. Ketoconazole, Clarithromycin, Itraconazole, Ritonavir)
  2. Avoid Tamsulosin with strong CYP2D6 Inhibitors (e.g. Fluoxetine)

VI. Resources

  1. Tamsulosin (DailyMed)
    1. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=bcd86877-5868-49dd-840b-7860b405fac7

VII. References

  1. Hamilton (2020) Tarascon Pharmacopoeia, Jones and Bartlett, Boston
  2. Nachawati (2022) Alpha Blockers, StatPearls, Treasure Island, FL, accessed 12/25/2022
    1. https://www.ncbi.nlm.nih.gov/books/NBK556066/

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Related Studies

Cost: Medications

tamsulosin (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
TAMSULOSIN HCL 0.4 MG CAPSULE Generic $0.06 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. GoodRx is another tool for finding lower drug prices.

Related Topics in Pharmacology

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