II. Indications
III. Dosing
- Start 0.4 mg orally daily
- Maximum 0.8 mg/day
IV. Adverse Effects
- See Selective Alpha-1a Antagonist
- Rare Sulfa Allergy cross-reactivity
- Postural Hypotension (esp. when combined with Antihypertensives)
- Floppy Iris Syndrome
- Ejaculatory Dysfunction (class effect)
V. Drug Interactions
- Avoid all Selective Alpha-1a Antagonists with strong CYP3A4 inhibitors (e.g. Ketoconazole, Clarithromycin, Itraconazole, Ritonavir)
- Avoid Tamsulosin with strong CYP2D6 Inhibitors (e.g. Fluoxetine)
VI. Resources
VII. References
- Hamilton (2020) Tarascon Pharmacopoeia, Jones and Bartlett, Boston
- Nachawati (2022) Alpha Blockers, StatPearls, Treasure Island, FL, accessed 12/25/2022
Images: Related links to external sites (from Bing)
Related Studies
tamsulosin (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
TAMSULOSIN HCL 0.4 MG CAPSULE | Generic | $0.06 each |
Ontology: tamsulosin (C0257343)
Definition (NCI_NCI-GLOSS) | A drug used to treat urinary problems caused by an enlarged prostate. Tamsulosin relaxes the muscles of the prostate and bladder, which helps the flow of urine. It is a type of alpha blocker. |
Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
MSH | C088482 |
SnomedCT | 108559004, 372509005 |
LNC | LP171642-4 |
English | 5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide, tamsulosin, 5-((2R)-2-(2-(2-ethoxyphenoxy)ethylamino)propyl)-2-methoxy-benzenesulfonamide, tamsulosin [Chemical/Ingredient], TAMSULOSIN, Tamsulosin, Tamsulosin (product), Tamsulosin (substance) |
Spanish | tamsulosina (producto), tamsulosina (sustancia), tamsulosina |
Ontology: Flomax (C0662903)
Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
MSH | C088482 |
English | Flomax, Abbott laboratories brand of tamsulosin hydrochloride, flomax |