II. Indications

  1. See Angiotensin Receptor Blocker
  2. Hypertension
  3. Cardiovascular Secondary Prevention

III. Contraindications

IV. Mechanism

V. Dosing: Adults

  1. Swallow whole tablets (do not break or crush)
  2. Hypertension or cardiovascular secondary prevention
    1. Start 40 mg orally daily
    2. Maximum 80 mg/day

VI. Adverse Effects

VII. Safety

  1. See Angiotensin Receptor Blocker
  2. Pregnancy Category X
  3. Unknown Safety in Lactation

VIII. Drug Interactions

  1. Digoxin
    1. Telmisartan may increase Digoxin levels

X. References

  1. (2018) Presc Lett, Resource #340901, Angiotensin Receptor Blocker (ARB) Antihypertensive Dose Comparison
  2. (2020) Med Lett Drugs Ther 62(1598): 73-80
  3. Olson (2020) Clinical Pharmacology, Medmaster Miami, p. 66-7
  4. Hamilton (2020) Tarascon Pocket Pharmacopoeia

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Related Studies

Cost: Medications

telmisartan (on 4/19/2023 at Medicaid.Gov Survey of pharmacy drug pricing)
TELMISARTAN 20 MG TABLET Generic $0.19 each
TELMISARTAN 40 MG TABLET Generic $0.26 each
TELMISARTAN 80 MG TABLET Generic $0.28 each
TELMISARTAN-AMLODIPINE 40-10 Generic $3.72 each
TELMISARTAN-AMLODIPINE 40-5 MG Generic $3.89 each
TELMISARTAN-AMLODIPINE 80-10 Generic $2.50 each
TELMISARTAN-AMLODIPINE 80-5 MG Generic $3.05 each
TELMISARTAN-HYDROCHLOROTHIAZIDE 40-12.5 MG TB Generic $0.66 each
TELMISARTAN-HYDROCHLOROTHIAZIDE 80-12.5 MG TB Generic $0.86 each
TELMISARTAN-HYDROCHLOROTHIAZIDE 80-25 MG TAB Generic $0.79 each
micardis (on 1/10/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
MICARDIS 80 MG TABLET Generic $0.28 each

Ontology: telmisartan (C0248719)

Definition (NCI) A benzimidazole derivative and a non-peptide angiotensin II receptor antagonist with antihypertensive property. Telmisartan selectively antagonizes angiotensin II binding to the AT1 subtype receptor, located in vascular smooth muscle and adrenal gland. The antagonism results in vasodilation and inhibits the angiotensin II-mediated aldosterone production, which in turn leading to a decrease in sodium and water as well as an increase in potassium excretion leading to a subsequent reduction in blood pressure.
Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH C084178
SnomedCT 318985000, 129487008, 387069000
LNC LP171643-2
English (1,1'-Biphenyl)-2-carboxylic acid, 4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-, 4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid, 4'-((4-Methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic Acid, (1,1'-Biphenyl)-2-carboxylic Acid, 4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-, telmisartan (medication), telmisartan, telmisartan [Chemical/Ingredient], TELMISARTAN, Telmisartan (product), Telmisartan (substance), Telmisartan
Spanish telmisartano (sustancia), telmisartano, telmisartán (producto), telmisartán (sustancia), telmisartán

Ontology: Micardis (C0721704)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH C084178
English Micardis, telmisartan (Micardis), micardis, Boehringer Ingelheim brand of telmisartan, Abbott brand of telmisartan