Irbesartan

Aka: Irbesartan, Avapro, Avalide

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II. Indications

  1. See Angiotensin Receptor Blocker
  2. Hypertension

III. Contraindications

  1. See Angiotensin Receptor Blocker

IV. Mechanism

  1. See Angiotensin Receptor Blocker

V. Dosing: Adults

  1. Hypertension or Diabetic Nephropathy
    1. Start 150 mg orally daily
    2. Start 75 mg orally daily in elderly, concurrent Diuretic use
  2. Maximum 300 mg/day

VI. Medications: Combinations

  1. Hydrochlorothiazide and Irbesartan (Avalide)

VII. Adverse Effects

  1. See Angiotensin Receptor Blocker

VIII. Safety

  1. See Angiotensin Receptor Blocker
  2. Pregnancy Category X
  3. Unknown Safety in Lactation

IX. Resources

  1. Irbesartan (DailyMed)
    1. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=2113a901-2612-4557-b86d-3afc006fb8bb

X. References

  1. (2018) Presc Lett, Resource #340901, Angiotensin Receptor Blocker (ARB) Antihypertensive Dose Comparison
  2. (2020) Med Lett Drugs Ther 62(1598): 73-80
  3. Olson (2020) Clinical Pharmacology, Medmaster Miami, p. 66-7
  4. Hamilton (2020) Tarascon Pocket Pharmacopoeia

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