III. Contraindications

IV. Mechanism

V. Dosing: Adults

  1. Hypertension or Diabetic Nephropathy
    1. Start 150 mg orally daily
    2. Start 75 mg orally daily in elderly, concurrent Diuretic use
  2. Maximum 300 mg/day

VI. Medications: Combinations

  1. Hydrochlorothiazide and Irbesartan (Avalide)

VII. Adverse Effects

VIII. Safety

  1. See Angiotensin Receptor Blocker
  2. Pregnancy Category X
  3. Unknown Safety in Lactation

X. References

  1. (2018) Presc Lett, Resource #340901, Angiotensin Receptor Blocker (ARB) Antihypertensive Dose Comparison
  2. (2020) Med Lett Drugs Ther 62(1598): 73-80
  3. Olson (2020) Clinical Pharmacology, Medmaster Miami, p. 66-7
  4. Hamilton (2020) Tarascon Pocket Pharmacopoeia

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Related Studies

Cost: Medications

irbesartan (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
IRBESARTAN 150 MG TABLET Generic $0.18 each
IRBESARTAN 300 MG TABLET Generic $0.24 each
IRBESARTAN 75 MG TABLET Generic $0.17 each
IRBESARTAN-HYDROCHLOROTHIAZIDE 150-12.5 MG TB Generic $0.19 each
IRBESARTAN-HYDROCHLOROTHIAZIDE 300-12.5 MG TB Generic $0.24 each
avapro (on 1/3/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
AVAPRO 150 MG TABLET Generic $0.18 each
AVAPRO 300 MG TABLET Generic $0.24 each