II. Interpretation
- Normal: <1.0 mg/dl
III. Causes: Increased (Unconjugated Hyperbilirubinemia)
- Increased Bilirubin production
- Large heme load (e.g. large Hematoma reabsorption)
- Rhabdomyolysis
- Hyperthyroidism (Thyrotoxicosis)
- Hemoglobinopathy (Thalassemia, Sickle Cell Anemia)
- Spherocytosis
- Hemolytic Anemia (typically mild Hyperbilirubinemia)
- Autoimmune Hemolytic Anemia
- Drug-Induced Hemolytic Anemia
- RBC enzyme disorders (e.g. G6PD Deficiency, pyruvate kinase deficiency, P5'N deficiency)
- Ineffective Erythropoiesis (increased RBC destruction in marrow)
- Pernicious Anemia
- Lead Poisoning
- Iron Deficiency Anemia
- Myeloproliferative Disorder
- Defective Bilirubin conjugation
- Neonatal Jaundice (immature liver)
- Gilbert's disease
- Crigler-Najjar syndrome
- Impaired hepatic uptake of Bilirubin
- Medications (e.g. Gemfibrozil, Indinavir)
- Portosystemic shunt
- Hepatic congestion (e.g .CHF, liver disease)
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Related Studies
Concepts | Disease or Syndrome (T047) |
MSH | D007565 , D000743 |
SnomedCT | 60217008 |
Dutch | geelzucht hemolytisch, hemolytische geelzucht, geelzucht; hemolytisch, hemolytisch; geelzucht, hemolytisch; icterus, icterus; hemolytisch, Icterus, hemolytische |
German | Gelbsucht haemolytisch, Ikterus, hämolytischer, Hämolytischer Ikterus, Icterus haemolyticus |
Portuguese | Icterícia hemolítica, Icterícia Hemolítica |
Spanish | Ictericia hemolítica, Ictericia Hemolítica, ictericia hemolítica (trastorno), ictericia hemolítica |
Japanese | 溶血性黄疸, ヨウケツセイオウダン |
Czech | Hemolytická žloutenka, Hemolytická icterus, žloutenka hemolytická |
English | Jaundice haemolytic, Jaundice hemolytic, jaundice hemolytic, Jaundice;haemolytic, hemolytic jaundice, Hemolytic Jaundices, Jaundice, Hemolytic, Jaundices, Hemolytic, Hemolytic jaundice, Haemolytic jaundice, Hemolytic jaundice (disorder), hemolytic; icterus, hemolytic; jaundice, icterus; hemolytic, jaundice; hemolytic, Hemolytic Jaundice, Jaundice;hemolytic, haemolytic jaundice |
Hungarian | Sárgaság haemolyticus, Sárgaság, haemolytikus |
French | Ictère hémolytique, Jaunisse hémolytique |
Italian | Ittero emolitico |
Ontology: Indirect reacting bilirubin (C0301719)
Concepts | Biologically Active Substance (T123) , Organic Chemical (T109) |
SnomedCT | 37852002, 79706000 |
English | Indirect reacting bilirubin, indirect bilirubin, bilirubin indirect, unconjugated bilirubin, Indirect (Unconjugated) Bilirubin, Unconjugated bilirubin, Indirect bilirubin, BU - Bilirubin, UCB - Unconjugated bilirubin, UCBR - Unconjugated bilirubin, Indirect reacting bilirubin (substance) |
Spanish | bilirrubina de reacción indirecta (sustancia), bilirrubina de reacción indirecta, bilirrubina no conjugada |