II. Indications

III. Mechanism

  1. Indicator of fecal Leukocyte activity

IV. Protocol

  1. Calprotectin is stable in stool samples at room Temperature for up to 1 week

V. Interpretation

  1. Negative test suggests diagnoses other than Inflammatory Bowel Disease are more likely
  2. Positive test requires Colonoscopy for confirmation

VI. Efficacy: Diagnosis of Inflammatory Bowel Disease

  1. Test Sensitivity: 93%
  2. Test Specificity
    1. Adults: 96%
    2. Children and Adolescents: 76%

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