II. Labs

  1. Normal: Titer<1:20

III. Causes: Positive (Titer >1:40)

  1. Primary Biliary Cirrhosis (85-90% of patients)
  2. Chronic active hepatitis (up to 25-30% of patients)
    1. Hepatitis CVirus (8% of patients)
  3. Cryptogenic Cirrhosis (25-30% of patients)
  4. Healthy patients without identified cause (<1%)

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