II. Preparations

  1. Bacitracin
  2. Mupirocin (Bactroban) 2% ointment
    1. Impetigo: Applied three times daily to affected area for 7-10 days
    2. May be used in age 2 months and older
    3. Available as 22 g tube (ointment is less expensive than creams)
    4. Emerging Streptococcal resistance in 2014
  3. Retapamulin (Altabax) 1% ointment
    1. Impetigo: Apply twice daily to affected area for 5 days
    2. May be used in age 9 months and older
    3. Treatment area must be <100 cm2 (or <2% total BSA in children)
  4. Fusidic Acid 2% cream (Not available in United States)
    1. Impetigo: Apply three times daily to affected area for 10-12 days
    2. Koning (2002) BMJ 324:203-6 [PubMed]

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Cost: Medications

bacitracin (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
BACITRACIN 500 UNIT/GM OINTMNT Generic OTC $0.07 per gram
BACITRACIN ZN 500 UNIT/GM OINT Generic OTC $0.07 per gram
BACITRACIN-POLYMYXIN EYE OINT Generic $2.64 per gram
mupirocin (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
MUPIROCIN 2% CREAM Generic $2.75 per gram
MUPIROCIN 2% OINTMENT Generic $0.17 per gram