Ergotamine

Aka: Ergotamine, Wigraine

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II. Indications

  1. Migraine Abortive Management

III. Dosing

  1. Sublingual
    1. One tab SL
    2. Repeat in 1/2 hour prn
    3. Maximum: 3/day or 6/week
    4. Oral tablets available
  2. Rectal Suppository (Wigraine)
    1. One rectally at Headache onset
    2. May repeat hourly
    3. Maximum: 2 suppositories per day or 12 per month
    4. Limit no more than 2 days per week
    5. May use for Menstrual Migraine

IV. Adverse Effects

  1. Nausea, Vomiting
    1. Use Antiemetic
  2. Rebound Headache
  3. Occluded vessel in Overdose
    1. Overdose levels
      1. Daily use exceeds 6 mg
      2. Weekly use exceeds 10 mg
    2. Potentiated by
      1. Beta Blockers
      2. Dopamine
      3. Fever
      4. Liver Disease

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Related Studies

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