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Ontology:
oxcarbazepine
(C0069751)
Definition (NCI)
|
A dibenzazepine carboxamide derivative with an anticonvulsant property. As a prodrug, oxcarbazepine is converted to its active metabolite, 10-monohydroxy. Although the mechanism of action has not been fully elucidated, electrophysiological studies indicate this agent blocks voltage-gated sodium channels, thereby stabilizing hyper-excited neural membranes, inhibiting repetitive neuronal firing, and decreasing the propagation of synaptic impulses.
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Concepts |
Pharmacologic Substance
(T121)
, Organic Chemical
(T109)
|
MSH |
C036006
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SnomedCT |
323042005, 116511002, 387025007 |
LNC |
LP20805-5, MTHU012038 |
English |
10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide, oxcarbazepine (medication), OXCARBAZEPINE, oxcarbazepine [Chemical/Ingredient], oxcarbazepine substance, OXcarbazepine, oxcarbazepine, Oxcarbazepine (product), Oxcarbazepine (substance), Oxcarbazepine |
Spanish |
oxcarbacepina, oxcarbazepina (producto), oxcarbazepina (sustancia), oxcarbazepina |
Ontology:
Trileptal
(C0876196)
Concepts |
Pharmacologic Substance
(T121)
, Organic Chemical
(T109)
|
MSH |
C036006
|
English |
trileptal, Novartis brand of oxcarbazepine, Trileptal |
Japanese |
オクスカルバゼピン
|