Dihydroergotamine

Aka: Dihydroergotamine, DHE-45

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II. Indications

  1. Migraine Abortive Management

III. Dosing

  1. Parenteral
    1. Initial: 1 mg SC/IM/IV over 3-4 minutes
    2. Repeat: May repeat every 1 hour
    3. Maximum: 3 mg/day, 6 mg/week, 20 mg/month
  2. Intranasal Dihydroergotamine (Migranal)

IV. Advantages

  1. Weaker Vasoconstrictor (less Side Effects)
  2. No Rebound Headache

V. Adverse Effects

  1. Retroperitoneal fibrosis

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Cost: Medications

dihydroergotamine (on 9/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
DIHYDROERGOTAMINE MESYLATE 4 MG/ML NASAL SPRAY Generic $147.05 per ml
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. GoodRx is another tool for finding lower drug prices.

Related Topics in Pharmacology

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