II. Epidemiology

  1. CDC is reporting 805 Vaping-related severe lung injury cases (and 10 deaths) as of 9/25/2019

III. Mechanisms

  1. Acute Interstitial Lung Disease
    1. Related to diacetyl, flavorings, and solvents
  2. Lipoid Pneumonia (from oil aspiration) with alveolar Macrophage infiltration
    1. Vitamin E and diacetyl-induced popcorn lung have also been seen with Vaping

IV. Symptoms

  1. Fever and chills
  2. Fatigue
  3. Non-productive cough
  4. Dyspnea
  5. Chest Pain
  6. Nausea
  7. Vomiting
  8. Abdominal Pain

VII. Imaging

  1. Chest XRay
    1. Infiltrates may be present
  2. CT Chest
    1. Ground glass opacities may be present

VIII. Management

  1. Hypoxia
    1. Supplemental Oxygen
    2. Noninvasive Positive Pressure Ventilation (e.g.BIPAP)
    3. Endotracheal Intubation
  2. Adjunctive
    1. High dose IV Corticosteroids
  3. Refractory, Critical Illness (e.g. cardiopulmonary collapse)
    1. ECMO

X. References

  1. Tomaszekski (2019) Crit Dec Emerg Med 33(10): 23

Images: Related links to external sites (from Bing)

Related Studies (from Trip Database) Open in New Window