II. Background: Street Names
- Roachies
- La Rocha
- Rope
- Rib Roche
- Roofies
- Ruffies
- Mexican Valium
- Rophies
- Forget-me pill
III. Indications
- Medical Uses
- Sedative-Hypnotic for Insomnia (Sleep aid)
- Pre-surgical Sedative
- Illicit Uses (widely available for legal purchase in Europe and Latin America)
- Calm down after Cocaine
- Date Rape Drug (5% of Date Rapes in U.S.)
IV. Pharmacokinetics
-
Benzodiazepine (similar to Versed)
- Relative potency to Valium: 10 fold more potent
- Typical Dosages: 1-2 mg
- Onset effect 20-30 minutes
- Peak effect 1-2 hours
-
Sedative Effect after 2 mg tab: 6-8 hours
- Duration longer when combined with Alcohol or drugs
- Dissolves in frothy drinks (Daiquiri, Margarita)
V. Effects
- Lower dose (1-2 mg)
- Relaxes skeletal Muscle and impairs motor skills
- Reduces inhibitions and impairs judgment
- Reduces anxiety
- Higher dose
- Appears Drunk
- Dizziness
- Confusion
- Amnestic effect (variable, may be over 24 hours)
- Loss or Altered Level of Consciousness
VI. Toxicology: Gas chromatography Urine Sample
- Metabolites detected up to 72 hours after 2 mg tablet
- Main metabolite: 7-amino-Flunitrazepam
- Needs to be sent to special lab
- Hoffmann-La Roche offers free testing
- General Info: 800-720-1076
- Testing: 800-608-6540
- Also detects
- Other Benzodiazepines
- Marijuana
- Cocaine
- Some Opiates
- Some Barbiturates
VII. Drug Interactions (may be lethal in combination)
VIII. Antidote
IX. References
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Related Studies
| Definition (MSH) | A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug. |
| Definition (PSY) | A benzodiazepine with sedative and hypnotic properties. |
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | D005445 |
| SnomedCT | 387573007, 96237009 |
| LNC | LP14357-5, MTHU008722 |
| English | Flunitrazepam, Fluridrazepam, 2H-1,4-Benzodiazepin-2-one, 5-(2-fluorophenyl)-1,3-dihydro-1-methyl-7-nitro-, flunitrazepam (medication), Flunitrazepam [Chemical/Ingredient], 2H-1,4-Benzodiazepin-2-One, 5-(2-Fluorophenyl)-1,3-Dihydro-1-Methyl-7-Nitro-, 5-(O-Fluorophenyl)-1,3-Dihydro-1-Methyl-7-Nitro-2H-1,4-Benzodiazepin-2-One, flunitrazepam, FLUNITRAZEPAM, Flunitrazepam (product), Flunitrazepam (substance) |
| Swedish | Flunitrazepam |
| Czech | flunitrazepam |
| Finnish | Flunitratsepaami |
| Russian | FLUNITRAZEPAM, FLURIDRAZEPAM, ФЛУНИТРАЗЕПАМ, ФЛУРИДРАЗЕПАМ |
| Japanese | フルリドラゼパム, フルニトラゼパム, ロヒプノル |
| Croatian | FLUNITRAZEPAM |
| Spanish | flunitracepam, flunitracepam (producto), flunitrazepam (producto), flunitracepam (sustancia), flunitrazepam (sustancia), flunitrazepam, Flunitrazepam, Fluridrazepam |
| Polish | Flunitrazepam |
| French | Flunitrazépam |
| German | Flunitrazepam, Fluridrazepam |
| Italian | Flunitrazepam |
| Portuguese | Flunitrazepam, Fluridrazepam |
Ontology: Rohypnol (C0699927)
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | D005445 |
| Portuguese | Rohipnol |
| Spanish | Rohipnol |
| German | Rohipnol |
| English | Rohypnol (not approved for use in U.S.), Rohypnol (not approved for use in U.S.) (medication), rohypnol, rohypnols, Rohypnol, Narcozep, Roche Brand of Flunitrazepam, Rohipnol |
