II. Definitions

  1. Limbic System
    1. Complex interconnected neural pathways in the Diencephalon and brainsterm related to emotion and motivation
    2. Integrates visceral, olfacory and somatic inputs
    3. Structures include
      1. Hippocampus
      2. Amygdala
      3. Epithalamus
      4. Gyrus cinguli
      5. Parahippocampal gyrus
      6. Hypothalamus
      7. Septal Nuclei
      8. Thalamic anterior nuclear group
  2. Septal Nuclei
    1. Grey matter in the septal region of brain inferior to corpus callosum, a part of the Telencephalon and Limbic System
    2. Septal Nuclei include dorsal, lateral, medial, triangular, septofimbrial, diagonal band, anterior commissure, stria terminalis

III. Physiology: Medial Limbic Circuit (Papez Circuit)

  1. Function
    1. Episodic Memory appears to be a core function of the Medial Limbic Circuit (Papez Circuit)
    2. Injury to the pathway is associated with Amnesia, Alzheimer's Disease, Wernicke-Korsakoff Syndrome
  2. Pathway (in order of signals)
    1. Hippocampal formation
    2. Fornix
    3. Mammillary Bodies
    4. Mammillothalamic Tract
    5. Anterior Thalamic Nucelus
    6. Cingulum
    7. Entorhinal Cortex
    8. Hippocampal formation

IV. Resources

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Related Studies

Ontology: Limbic System (C0023715)

Definition (NCI_NCI-GLOSS) A network of structures in the brain involved in memory and emotions.
Definition (CSP) group of brain structures associated with olfaction but of greater importance in other activities, such as autonomic functions and aspects of emotion and behavior.
Definition (MSH) A set of forebrain structures common to all mammals that is defined functionally and anatomically. It is implicated in the higher integration of visceral, olfactory, and somatic information as well as homeostatic responses including fundamental survival behaviors (feeding, mating, emotion). For most authors, it includes the AMYGDALA; EPITHALAMUS; GYRUS CINGULI; hippocampal formation (see HIPPOCAMPUS); HYPOTHALAMUS; PARAHIPPOCAMPAL GYRUS; SEPTAL NUCLEI; anterior nuclear group of thalamus, and portions of the basal ganglia. (Parent, Carpenter's Human Neuroanatomy, 9th ed, p744; NeuroNames, http://rprcsgi.rprc.washington.edu/neuronames/index.html (September 2, 1998)).
Concepts Body System (T022)
MSH D008032
SnomedCT 58590008
English Limbic Systems, System, Limbic, Systems, Limbic, limbic system, Limbic system, Limbic system structure (body structure), Limbic system structure, Limbic System
Swedish Limbiska systemet
Czech limbický systém
Finnish Limbinen järjestelmä
Russian MOZG OBONIATEL'NYI, LIMBICHESKAIA SISTEMA, ЛИМБИЧЕСКАЯ СИСТЕМА, МОЗГ ОБОНЯТЕЛЬНЫЙ
Croatian LIMBIČKI SUSTAV
Latvian Limbiskā sistēma
Polish Układ limbiczny
Norwegian Det limbiske system, limbiske system
Spanish encéfalo visceral, estructura del sistema límbico (estructura corporal), estructura del sistema límbico, sistema límbico, Sistema Límbico
French Système limbique
German Limbisches System
Italian Sistema limbico
Dutch Limbisch systeem, Systeem, limbisch
Portuguese Sistema Límbico

Ontology: Septal Nuclei (C0036687)

Definition (FMA) Subdivision of the septum which contains the dorsal septal nucleus, the lateral septal nucleus, medial septal nucleus, triangular septal nucleus, septofimbrial nucleus, nucleus of diagonal band, nucleus of anterior commissure and nucleus of stria terminalis.
Definition (MSH) Neural nuclei situated in the septal region. They have afferent and cholinergic efferent connections with a variety of FOREBRAIN and BRAIN STEM areas including the HIPPOCAMPAL FORMATION, the LATERAL HYPOTHALAMUS, the tegmentum, and the AMYGDALA. Included are the dorsal, lateral, medial, and triangular septal nuclei, septofimbrial nucleus, nucleus of diagonal band, nucleus of anterior commissure, and the nucleus of stria terminalis.
Definition (PSY) Subcallosal nuclei that form an integral part of the limbic system. These nuclei contribute to the medial forebrain bundle and have processes synapsing in the hippocampus.
Concepts Body Part, Organ, or Organ Component (T023)
MSH D012686
English Nuclei, Septal, Septal Nuclei, Parolfactory nuclei, Septal nuclei, Septal nuclear complex, Nuclei septaeis, Septal nuclei set, Set of septal nuclei, Septal nuclei and related structures, parolfactory nuclei, septal nuclei, SptN, nuclei septi, Nuclei septales, Complices, Septal Nuclear, Nuclear Complices, Septal, Septal Nuclear Complex, Septal Nuclear Complices, Complex, Septal Nuclear, Nuclear Complex, Septal
French Noyaux du septum, Noyaux du septum pellucidum
Swedish Septala kärnor
Czech septum pellucidum - jádra
Finnish Septumtumakkeet
Russian MOZG GOLOVNOI, PEREGORODKI IADRA, PROMEZHUTOCHNYI MOZG, PEREGORODKI IADRA, PEREGORODKI MOZGA IADRA, MOZGA GOLOVNOGO PEREGORODKI IADRA, IADRA PEREGORODKI GOLOVNOGO MOZGA, МОЗГА ГОЛОВНОГО ПЕРЕГОРОДКИ ЯДРА, МОЗГ ГОЛОВНОЙ, ПЕРЕГОРОДКИ ЯДРА, ПЕРЕГОРОДКИ МОЗГА ЯДРА, ПРОМЕЖУТОЧНЫЙ МОЗГ, ПЕРЕГОРОДКИ ЯДРА, ЯДРА ПЕРЕГОРОДКИ ГОЛОВНОГО МОЗГА
Japanese 中隔核, 対角帯核, 中隔核群
Polish Jądra przegrody
Norwegian Septumkjerner, Septale kjerner
German Septumkerne
Italian Nuclei settali
Dutch Kern, septum-, Septumkern, Septumkernen
Portuguese Núcleos Septais
Spanish Núcleos Septales