II. Diagnosis
- Complaint of Memory Loss and impaired for age
- Significant Forgetfulness
- Does not meet criteria for Dementia
- Normal general cognitive functioning
- Normal Activities of Daily Living
III. Differential Diagnosis
IV. Evaluation
- See Mental Status Exam
- Routine screening of asymptomatic older patients is not currently recommended by USPTF
V. Diagnostics
VI. Management
- Lifestyle interventions may be helpful
- Encourage mentally stimulating activities
- Unclear efficacy of mentally challenging puzzles (e.g. crossword puzzles, Soduko), but may be helpful
- Encourage social engagement
- Increase Physical Activity
- Address Cardiac Risk Factors
- Avoid medications
- Avoid using Cholinesterase Inhibitors or Nemenda for Mild Cognitive Impairment
- Associated with adverse effects without evidence of benefit
- No evidence for consistent benefit from any herbal supplement (e.g. ginkgo, coconut oil)
- No consistent evidence for Multivitamin supplementation (although unlikely to be harmful)
- Avoid using Cholinesterase Inhibitors or Nemenda for Mild Cognitive Impairment
VII. Course
- Improves spontaneously in up to 50% of cases
- May ultimately progress with age to Alzheimer's Dementia
- Progresses in 5-10% of patients/year compared with 1-2% without Mild Cognitive Impairment