II. Indications

  1. Solid Organ Transplant Immunosuppression (maintenance prevention of rejection)

III. Adverse Effects: Mycophenolate or Mycophenolic acid

  1. See Azathioprine (Imuran)
  2. Bone Marrow suppression
  3. Gastrointestinal adverse effects (e.g. Nausea, Vomiting, Diarrhea, Abdominal Pain)

IV. Preparations

  1. Azathioprine (Imuran)
  2. Mycophenolate (Cellcept)
  3. Mycophenolic acid (MyFortic)

V. Drug Interactions

  1. See Cytochrome P-450 3A4
  2. Agents that increase Purine Synthesis Inhibitor concentrations
    1. Linezolid
    2. Valganciclovir (Valcyte) potentiates myelosuppression
    3. Allopurinol (esp. Azathioprine)
  3. Agents that decrease Purine Synthesis Inhibitor concentrations
    1. Rifampin

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Related Studies

Cost: Medications

mycophenolate (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
MYCOPHENOLATE 200 MG/ML SUSP Generic $3.12 per ml
MYCOPHENOLATE 250 MG CAPSULE Generic $0.19 each
MYCOPHENOLATE 500 MG TABLET Generic $0.30 each
cellcept (on 7/19/2023 at Medicaid.Gov Survey of pharmacy drug pricing)
CELLCEPT 200 MG/ML ORAL SUSP Generic $3.12 per ml
mycophenolic acid (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
MYCOPHENOLIC ACID DR 180 MG TB Generic $0.24 each
MYCOPHENOLIC ACID DR 360 MG TB Generic $0.39 each