II. Indications
- Postherpetic Neuralgia (or other localized peripheral neuropathic pain)
- Other localized pain (e.g. Musculoskeletal Low Back Pain)
III. Contraindications
- Avoid in severe liver disease (higher toxicity risk)
IV. Precautions
- Avoid measures that increase systemic absorption, toxicity (e.g. LAST Reaction, Seizures, Arrhythmia)
- Do NOT use under Occlusion (e.g. overlying dressing)
- Limit application to unbroken skin only
- Do not apply with heat (e.g. electric blanket)
V. Medications
VI. Dosing
- Apply one patch to affected area for no more than 12 hours
- Remove patch, and maintain 12 hours free of Lidocaine before applying the next patch
- Apply a new patch for 12 of every 24 hours as needed
VII. Adverse Effects
- Application site reactions (e.g. Contact Dermatitis)
- Allergic Reaction (rare)
- Systemic toxicity if significant absorption (see precautions above)
- See Lidocaine
- See LAST Reaction
VIII. Safety
- Pregnancy category B
- Unknown safety in Lactation
IX. Resources
- Lidocaine Patch (DailyMed)
X. References
- (2017) Presc Lett 24(11):13
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Related Studies
lidoderm (on 1/1/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
LIDODERM 5% PATCH | Generic | $1.78 each |
Ontology: Lidocaine Transdermal Patch (C1251704)
Definition (NCI) | A transdermal patch containing a 5 percent aqueous base solution of the synthetic amide-type anesthetic lidocaine with analgesic activity. Upon topical application and transdermal delivery, the active ingredient lidocaine binds to and blocks voltage-gated sodium channels in the neuronal cell membrane; lidocaine-mediated stabilization of neuronal membranes inhibits the initiation and conduction of nerve impulses and produces a reversible local anesthesia. |
Concepts | Clinical Drug (T200) |
English | Lidocaine Transdermal Patch, Lidocaine Patch |