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Ontology:
Lidocaine Transdermal Patch
(C1251704)
Definition (NCI)
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A transdermal patch containing a 5 percent aqueous base solution of the synthetic amide-type anesthetic lidocaine with analgesic activity. Upon topical application and transdermal delivery, the active ingredient lidocaine binds to and blocks voltage-gated sodium channels in the neuronal cell membrane; lidocaine-mediated stabilization of neuronal membranes inhibits the initiation and conduction of nerve impulses and produces a reversible local anesthesia.
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Concepts |
Clinical Drug
(T200)
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English |
Lidocaine Transdermal Patch, Lidocaine Patch |