II. Indications
- Brief Procedural Sedation
- Rare use in U.S. now (other agents are preferred)
- Ideal for CT Head (brief action, Seizure Prophylaxis)
- May be accompanied to CT with RN (low risk of respiratory depression, or other serious adverse effects)
III. Mechanism
IV. Dosing: Procedural Sedation
- Dose: 2.5 mg/kg IV up to 100 mg (maximum administration rate 50 mg/min)
- May repeat additional 1.25 mg/kg as needed twice
- Observe for Hypotension
V. Adverse Effects
VI. Safety
- Pregnancy Category D
- Unknown safety in Lactation
VII. Resources
- Pentobarbital (DailyMed)