II. Mechanism

  1. Similar to Zeolite Mineral Dressing
  2. Topical Hemostatic Agent
  3. Aluminum silicate activates Intrinsic Clotting Pathway
  4. Increases Clotting Factor and Platelet concentration at wound sites via water absorption

III. Efficacy

  1. Slower control of bleeding
  2. Significantly increased survival in animal models
  3. May be less effective coagulopathic patients

IV. Advantages

  1. Available as gauze rolls (3 inch wide, 4 yard long)
  2. Combat Gauze is now primary hemostatic agent used on battlefield
  3. Some prefer on wounds not amenable to Tourniquet (e.g. high femoral wound)

V. References

  1. Mason, Spangler and Nichols (2016) EM:Rap 16(11): 10-11
  2. Kheirabadi (2011) US Army Med Dep J p. 25-37
  3. Swaminathan and van de Leuv (2013) Crit Dec in Emerg Med 27(8): 11-17

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Ontology: Kaolin (C0022499)

Definition (MSHCZE) Směs jílovitých nerostů, kaolinitu a gelovitých alumosilikátů, mj. plnivo medicinálních past a prášků. (cit. Velký lékařský slovník online, 2013 http://lekarske.slovniky.cz/ )
Definition (MSH) The most common mineral of a group of hydrated aluminum silicates, approximately H2Al2Si2O8-H2O. It is prepared for pharmaceutical and medicinal purposes by levigating with water to remove sand, etc. (From Merck Index, 11th ed) The name is derived from Kao-ling (Chinese: "high ridge"), the original site. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Concepts Pharmacologic Substance (T121) , Inorganic Chemical (T197)
MSH D007616
SnomedCT 398836001, 349807006, 87466002
English Kaolin, China clay, Native hydrated aluminum silicate, Argilla, Bolus alba, Native hydrated aluminium silicate, kaolin (medication), Bolus Alba, Porcelan Clay, China Clay, Weisserton, Clay 347, White Bole, Hydrated Aluminum Silicate, Kaolin [Chemical/Ingredient], bolus alba, KAOLIN, kaolin, Native hydrated aluminum silicate (substance), Kaolin product, Kaolin (substance), Kaolin product (product), Kaolin product (substance)
Swedish Kaolin
Czech kaolin
Finnish Kaoliini
Japanese 陶土, 白陶土, カオリナイト, カオリン
Spanish caolín (producto), producto con caolín (producto), producto con caolín, bolus alba, arcilla, silicato de aluminio hidratado nativo, arcilla blanca, kaolín, arcilla china, silicato de aluminio hidratado nativo (sustancia), Caolinita, caolín (sustancia), caolín, producto (producto), caolín, producto (sustancia), caolín, producto, caolín, kaolin, producto, Caolín
Polish Glinka biała, Kaolin
Norwegian Kaolin
Portuguese Caulinita, Caolino, Caolim, Caulim
French Kaolin
German Kaolin
Italian Caolino