Thrombin Hemostatic

Aka: Thrombin Hemostatic, Topical Thrombin, Topical Thrombin in Gelatin, Floseal

advertisement

II. Indications

  1. Control of minor bleeding (e.g. Tongue Laceration) in patients with prolonged INR (e.g. Warfarin)
  2. Used in combination with gelatins

III. Mechanism

  1. Topical Hemostatic Agent
  2. Thrombin facilitates Fibrinogen conversion to Fibrin in the formation of clot

IV. Preparations

  1. Bovine-derived Thrombin (Thrombin-JMI)
    1. Contraindicated in cow allergies
  2. Human plasma-derived Thrombin (Evithrom)
  3. Recombinant human Thrombin (rhThrombin)
  4. Topical Thrombin in Gelatin (Floseal)

V. References

  1. Berry in Schrage (2013) Topical Hemostatic Agents, Medscape Emedicine
  2. Peralta in Sanfrey (2013) Overview of Topical Hemostatic Agents and tissues adhesives used in the operating room, UpToDate, Wolters-Kluwer
  3. Achneck (2010) Ann Surg 251(2):217-28 [PubMed]

Images: Related links to external sites (from Bing)

These images are a random sampling from a Bing search on the term "Thrombin Hemostatic." Click on the image (or right click) to open the source website in a new browser window. Search Bing for all related images

Related Studies

Related Topics in Pharmacology

advertisement