II. Background
- Derived from Chitin is shellfish exoskeletons
III. Mechanism
- Topical Hemostatic Agent
- Local Vasoconstriction
- Mobilizes Clotting Factors and Platelets
- Mechanical sealing
IV. Efficacy
- Stops bleeding in 97% of wounds not stopped with direct pressure
- However, bleeding restarts within 1 hour in up to 70% of cases (and nearly all arterial Hemorrhage)
V. References
- Kheirabadi (2011) US Army Med Dep J p. 25-37
- Swaminathan and van de Leuv (2013) Crit Dec in Emerg Med 27(8): 11-17
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Definition (NCI_NCI-GLOSS) | A type of polysaccharide (sugar molecule) that is made by some plants and animals. The hard outer shell of shrimp, lobsters, and many insects is made of chitin. |
Definition (MSH) | A linear polysaccharide of beta-1->4 linked units of ACETYLGLUCOSAMINE. It is the second most abundant biopolymer on earth, found especially in INSECTS and FUNGI. When deacetylated it is called CHITOSAN. |
Definition (CSP) | tough, white polysaccharide of acetylglucosamine found in arthropod shells and elsewhere; the second most abundant polysaccharide in nature, after cellulose. |
Concepts | Biologically Active Substance (T123) , Carbohydrate (T118) |
MSH | D002686 |
English | Chitin, Chitin [Chemical/Ingredient], chitin |
Swedish | Kitin |
Czech | chitin |
Finnish | Kitiini |
Russian | KHITIN, ХИТИН |
Polish | Chityna |
French | Chitine |
German | Chitin |
Italian | Chitina |
Portuguese | Quitina |
Spanish | Quitina |
Ontology: Chitosan (C0162969)
Definition (MSH) | Deacetylated CHITIN, a linear polysaccharide of deacetylated beta-1,4-D-glucosamine. It is used in HYDROGEL and to treat WOUNDS. |
Concepts | Pharmacologic Substance (T121) , Carbohydrate (T118) |
MSH | D048271 |
English | CHITOSAN @ @ UNIDENTIFIED, CHITOSAN UNIDENTIFIED, Chitosan [Chemical/Ingredient], CHITOSAN, chitosans, chitosan, Chitosan, Poliglusam |
Swedish | Kitosan |
Czech | chitosan |
Finnish | Kitosaani |
Russian | KHITOZAN, ХИТОЗАН |
Japanese | キトサン, ポリグルサム |
Italian | Poliglusam, Chitosano |
Polish | Chitosan |
Spanish | Quitosano, Quitosana, Chitosán, Quitosán |
Portuguese | Quitosano, Quitosana |
French | Chitosane, Chitosan, Polymères de chitine désacétylée |
German | Chitosan, Poliglusam |