II. Background
- Dermatophagoides pteronyssinus
- Acaridae family (closely related to Spiders)
- Size 0.3 mm in length
- Eat human skin scales
- Conditions for growth
- Temperature: 21 C or 70 F
- Relative Humidity: 70%
III. Pathophysiology
- Most important indoor allergen
- Sensitivity predicts Asthma severity and development
- Exposure also related to other atopic disease
-
Antigen Sensitization to Der p1
- Der P1 found in Dust mite feces
- Feces are large (10 um) but still easily airborne
- Sites in home with high level of Dust mites
- Pillows and mattresses
- Bed is most significant source of exposure
- Carpets
- Drapes and upholstered furniture
- Clothing
- Pillows and mattresses