II. Management: General Approach
- See Pediatric Depression
- See Antepartum Depression
- See Depression in Athletes
- See Depression in Older Adults
- See Postpartum Major Depression
- Mild to Moderate Depression (PHQ-9 <16)
- Antidepressants (e.g. SSRI) are optional (per patient preference)
- Active monitoring of depression
- Consider Cognitive Behavioral Therapy
- Individual or group therapy
- Group Exercise
- Severe Depression (PHQ-9 >=16)
- Antidepressants (e.g. SSRI, SNRI) AND
- Cognitive Behavioral Therapy
III. Management: Medications
IV. Management: Psychotherapy - Reassurance and listening
- Instill hope
- Reframe depression as an adaptation to a patient's environment and circumstances
- Adaptation reframing destigmatizes depression and may help empower patient self-efficacy
- Think of depression as an alarm, alerting patients that something in their life needs attention
- Schroder (2023) Soc Sci Med 328: 115995 [PubMed]
- Consider Cork Analogy
- Think of self as cork under water
- No matter how much people or events push you under
- Eventually you will pop up
V. Management: Psychotherapy - Reinforce Positive Behaviors
-
Exercise (may increase energy and self esteem)
- Likely effective adjunct, although variable evidence (needs more high quality studies)
- Most effective when given as a formal Exercise Prescription
- Specify the frequency, intensity, duration and Exercise type
- Blumenthal (1999) Arch Intern Med 159:2349-56 [PubMed]
- Cooney (2014) JAMA 311(23): 2432-33 [PubMed]
- Dunn (2005) Am J Prev Med 28:1-8 [PubMed]
- Noetel (2024) BMJ 384:e075847 [PubMed]
- Yoga
- Effective in the treatment of Major Depression
- Cramer (2017) J Affect Disord 213:70-77 [PubMed]
-
Mindfulness Based Interventions
- Effective in the treatment of Major Depression
- Goldberg (2018) Clin Psychol Rev 59: 52-60 [PubMed]
-
Healthy Diet
- High fruit and vegetable intake is associated with decreased depression risk in age >45 years
- Attending Counseling
-
Antidepressant Compliance
- Reassure that these are not habit forming
- Reassure that these are not forever
- Establish a therapeutic alliance
- Schedule pleasurable activities (esp. with people)
- Repair relationships with family and friends
- Consider keeping a journal
VI. Management: Psychotherapy - Discourage Negative Behaviors
- Challenge negative thoughts
- Sleep disturbance
- Stress in relationships and work
- Poor diet or nutrition
- Alcohol use or Alcohol Abuse
- Medications that worsen depression (Beta Blockers)
VII. Management: Psychotherapy - Educate family and patient
- Greatest risk of Suicide is in early treatment
VIII. Management: Cognitive Behavioral Therapy
- Efficacy
- At least as effect as pharmacotherapy
- Wampold (2002) J Affect Disord 68:159-65 [PubMed]
- Summary of Process
- Recognize that some Perceptions of reality are false
- False Perceptions lead to negative thoughts
- Learn to identify negative thoughts as they occur
- Replace distorted thoughts with alternatives
- Reframe central beliefs about world and self-image
- Techniques
- Keep a Thought Journal
- Identify specific stressful situations
- Example: Meeting a new person
- Characterize associated mood and automatic reaction
- Example: I am anxious - they will hate me
- Identify reasons for negative thoughts
- Example: Noone speaks with me at parties
- Identify counter-arguments
- Example: I have close friends who care about me
- Substitute negative thought with alternative
- Example: I am likeable - be myself
- Identify specific stressful situations
- Set goals and activities (example follows)
- Goal: Exercise every day, this improves self-esteem
- Start: Next thursday, before work
- Obstacles: Early wake-up
- Strategies to overcome obstacles
- Be in bed by 10 pm, with clothes set out for AM
- Progress
- Jan 4: Arrived gym 20 minutes late, short jog
- Jan 5: Overslept, missed workout, bad day
- Jan 6: Swam for 40 minutes, feel great
- Keep a Thought Journal
IX. Management: Adjuncts
- Audio tape based Patient Education
- Small British study of "Coping with Depression" tape
- Found to effective adjunct to Depression Management
- Blenkiron (2001) Br J Gen Pract 51:366-70 [PubMed]
- Website based cognitive-behavioral management
- Mood Gym
- Effective in Major Depression