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Definition (MSHCZE)
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Paraneoplastický stav provázející malobuněčný bronchogenní karcinom plic připomínající klinicky myastenii (pseudomyastenie). Paraneoplastický syndrom charakterizovaný nervosvalovými poruchami a vegetativní dysfunkcí, svalová slabost, hyporeflexie, ptóza, xerostomie, ortostatická hypotenze, trávicí obtíže aj.. Podstatou je vznik autoprotilátek proti iontovým kanálům. (cit. Velký lékařský slovník online, 2013 http://lekarske.slovniky.cz/ )
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Definition (NCI)
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A rare autoimmune presynaptic disorder characterized by impairment of the impulse transmission at the neuromuscular junction. It affects predominantly the proximal muscles of the lower extremities, resulting in muscle weakness and fatigability. It has been associated with small cell lung carcinoma.
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Definition (MSH)
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An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471)
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| Concepts |
Disease or Syndrome
(T047)
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| MSH |
D015624
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| ICD9 |
358.3 |
| ICD10 |
G73.1
, G70.80 |
| SnomedCT |
230688006, 56989000 |
| English |
Eaton Lambert Myasthenic Syndrome, Eaton Lambert Syndrome, Eaton-Lambert Myasthenic Syndrome, Eaton-Lambert Syndrome, Lambert Eaton Syndrome, Lambert-Eaton Myasthenic Syndrome, Lambert-Eaton Syndrome, Myasthenic Syndrome, Eaton-Lambert, Myasthenic Syndrome, Lambert-Eaton, Syndrome, Eaton-Lambert Myasthenic, Syndrome, Lambert-Eaton, Syndrome, Lambert-Eaton Myasthenic, Syndrome, Eaton-Lambert, Eaton Lamb myasthenic syndr, Eaton Lambert myasthenic syndrome, LEMS - Lambrt-Eatn myasth synd, Lambert-Eaton myasthenic syndr, MYOPATHIC MYASTHENIC SYNDROME OF LAMBERT EATON, MYASTHENIC MYOPATHIC SYNDROME LAMBERT EATON, Myasthenic Syndrome, Lambert Eaton, Eaton-Lambert syndrome (diagnosis), Eaton-Lambert Myasthenic-Myopathic Syndrome, Eaton-Lambert Myopathic-Myasthenic Syndrome, Lambert-Eaton Myasthenic-Myopathic Syndrome, Lambert-Eaton Myopathic-Myasthenic Syndrome, Myasthenic-Myopathic Syndrome of Eaton-Lambert, Myasthenic-Myopathic Syndrome of Lambert-Eaton, Myopathic-Myasthenic Syndrome of Eaton-Lambert, Myopathic-Myasthenic Syndrome of Lambert-Eaton, Lambert-Eaton Myasthenic Syndrome [Disease/Finding], eaton lambert syndrome, myasthenic syndrome, eaton-lambert syndrome, lambert-eaton syndrome, lambert eaton syndrome, myasthenic syndromes, Eaton Lambert syndrome, Lambert Eaton myasthenic syndrome, Lambert Eaton syndrome, myasthenic syndrome of Lambert Eaton, Lambert-Eaton Myasthenic-Myopathic Syndromes, Myasthenic Myopathic Syndrome of Eaton Lambert, Myasthenic Myopathic Syndrome of Lambert Eaton, Myopathic Myasthenic Syndrome of Eaton Lambert, Lambert-Eaton syndrome, Lambert-Eaton Myopathic-Myasthenic Syndromes, Eaton-Lambert Myopathic-Myasthenic Syndromes, Lambert-Eaton syndrome NOS, Eaton Lambert myasthenic syndrome (disorder), Eaton-Lambert syndrome, LEMS - Lambert-Eaton myasthenic syndrome, Lambert-Eaton myasthenic syndrome, Myasthenic syndrome, Eaton-Lambert syndrome (disorder), Lambert-Eaton (etiology), Lambert-Eaton (manifestation), Eaton-Lambert (etiology), Eaton-Lambert (manifestation), Lambert Eaton Myasthenic Syndrome |
| French |
Syndrome myasthénique d'Eaton-Lambert, Syndrome de Lambert-Eaton, Syndrome myasthénique de Lambert-Eaton |
| Swedish |
Lambert-Eaton myastent syndrom
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| Czech |
Lambertův-Eatonův myastenický syndrom, Lambert-Eatonův syndrom, Lambert-Eatonův myastenický syndrom, Eatonův-Lambertův syndrom, LEMS, Lambertův-Eatonův-Rookeho syndrom, Lambertův-Eatonův syndrom |
| Spanish |
Síndrome miasténico de Eaton-Lambert, síndrome de Eaton - Lambert (trastorno), síndrome de Eaton - Lambert, síndrome miasténico, Síndrome de Eaton-Lambert, Síndrome de Lambert-Eaton Miasténico, Síndrome Miasténico de Lambert-Eaton |
| Dutch |
myastheen syndroom van Lambert-Eaton, Eaton-Lambert-syndroom, Lambert-Eaton-syndroom, Myasthenisch syndroom, Eaton-Lambert, Syndroom van Eaton-Lambert |
| Portuguese |
Síndrome miasténico de Eaton-Lambert, Síndrome de Eaton-Lambert, Síndrome Miastênica de Lambert-Eaton |
| German |
Lambert-Eaton Syndrom, Lambert-Eaton-Syndrom, Eaton-Lambert-Syndrom, Lambert-Eaton-Myasthenie-Syndrom, Myasthenie-Syndrom, Lambert-Eaton- |
| Japanese |
ランバート・イートン筋無力症候群, ｲｰﾄﾝﾗﾝﾊﾞｰﾄｼｮｳｺｳｸﾞﾝ, イートン・ランバート症候群, ﾗﾝﾊﾞｰﾄｲｰﾄﾝｷﾝﾑﾘｮｸｼｮｳｺｳｸﾞﾝ, イートン･ランバート症候群, ランバート･イートン症候群, Eaton-Lambert症候群, Lambert-Eaton症候群, Lambert-Eaton筋無力症候群, Lambert-Eaton筋無力症症候群, ランバート-イートン筋無力症症候群, 筋無力症症候群, ランバート-イートン症候群 |
| Finnish |
Myasteeninen oireyhtymä
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| Russian |
ITONA-LAMBERTA SINDROM, LAMBERTA-ITONA MIASTENICHESKII SINDROM, ИТОНА-ЛАМБЕРТА СИНДРОМ, ЛАМБЕРТА-ИТОНА МИАСТЕНИЧЕСКИЙ СИНДРОМ |
| Italian |
Sindrome di Eaton-Lambert, Sindrome miastenica di Eaton-Lambert, Sindrome miopatico miastenica di Eaton-Lambert, Sindrome miopatico miastenica di Lambert-Eaton, Sindrome di Lambert-Eaton, Sindrome miastenica di Lambert-Eaton |
| Korean |
이튼-람베르트 증후군
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| Polish |
Zespół miasteniczny Lamberta-Eatona, Zespół Lamberta-Eatona |
| Hungarian |
Eaton-Lambert-syndroma, Lambert-Eaton myastheniás syndroma |
| Norwegian |
Lambert-Eaton myastenisk syndrom, Eaton-Lambert syndrom |
