II. Risk Factors: Impacts mobility and stair climbing after ICU admit
- Prolonged ICU Stay
- Poor baseline health status
- Longer duration of Mechanical Ventilation
III. Pathophysiology
- Similar pathophysiology to Critical Illness Polyneuropathy
- Muscular deconditioning due to prolonged immobilization
- Myosin to Actin ratio reduced
- Lean Body Mass drops 2% per day with prolonged immobilization
IV. Diagnosis
- Similar diagnostic criteria for Critical Illness Polyneuropathy
- Limb Weakness AND
- Unexplained difficult mechanical Ventilator Weaning
V. Diagnostics
- Distinguish from Critical Illness Polyneuropathy
- Distinguish from other Myopathy
- Muscle Biopsy
VI. Management
- Physical Rehabilitation
- Contrast with Critical Illness Polyneuropathy in which physical therapy has no evidence of benefit
- Graded Exercise program
- Early mobilization is key
VII. Course
- Complications associated with deconditioning can persist 12 months after ICU admission
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Related Studies
| Concepts | Disease or Syndrome (T047) |
| ICD9 | 359.81 |
| ICD10 | G72.81 |
| SnomedCT | 443819006 |
| English | critical illness myopathy, critical illness myopathy (diagnosis), Critical illness myopthy, Critical illness myopathy, Critical illness myopathy (disorder), Myopathy of critical illness, critical illness myopathies, myopathy of critical illness, myopathy critical illness |
| Spanish | miopatía en dolencia crítica (trastorno), miopatía en dolencia crítica, Miopatía del paciente crítico |
| Czech | Myopatie kriticky nemocných |
| Dutch | kritieke ziekte myopathie |
| French | Myopathie de maladie critique |
| German | Critical-Illness-Myopathie |
| Hungarian | Myopathia kritikus betegségben |
| Italian | Miopatia da malattia critica |
| Japanese | 重症疾患ミオパチー, ｼﾞｭｳｼｮｳｼｯｶﾝﾐｵﾊﾟﾁｰ |
| Portuguese | Miopatia de doença crítica |
