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Definition (NCI)
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Expressed as 2 alternative isoforms in Sertoli cells and liver by human SHBG Gene, 402-aa 44-kDa (precursor) homodimeric Sex Hormone-Binding Globulin is a secreted beta-globulin plasma glycoprotein containing 2 laminin G-like domains that specifically bind 5-alpha-dihydrotestosterone, testosterone, or 17-beta-estradiol. An androgen transport protein, SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling plasma concentration and may be involved in receptor-mediated processes as well. (NCI)
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Definition (MSH)
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A glycoprotein migrating as a beta-globulin. Its molecular weight, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds testosterone, dihydrotestosterone, and estradiol in the plasma. Sex hormone-binding protein has the same amino acid sequence as ANDROGEN-BINDING PROTEIN. They differ by their sites of synthesis and post-translational oligosaccharide modifications.
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| Concepts |
Biologically Active Substance
(T123)
, Amino Acid, Peptide, or Protein
(T116)
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| MSH |
D012738
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| SnomedCT |
55503002
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| LNC |
LP15863-1, MTHU004559 |
| English |
Binding Globulin, Testosterone-Estradiol, Globulin, Sex Hormone-Binding, Globulin, Testosterone-Estradiol Binding, Hormone-Binding Globulin, Sex, Sex Hormone Binding Globulin, Sex Hormone-Binding Globulin, Sex Steroid Binding Protein, Sex Steroid-Binding Protein, Steroid-Binding Protein, Sex, Testosterone-Estradiol Binding Globulin, SHBG- Sex horm bind globulin, Sex Hormone-Binding Globulin [Chemical/Ingredient], sex hormone binding globulin, sex hormone-binding globulin, sex hormone binding globulin (SHBG), shbg, GBG, Sex hormone binding globulin, Sex steroid binding globulin, SHBG - Sex hormone binding globulin, Sex steroid binding globulin (substance), Testosterone Estradiol Binding Globulin, SHBG, Testis-Specific Androgen-Binding Protein |
| Swedish |
Könshormonbindande globulin
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| Czech |
globulin vážící pohlavní hormony
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| Finnish |
Sukupuolihormoneja sitova globuliini
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| Russian |
TESTOSTERON-ESTRADIOL-SVIAZYVAIUSHCHII GLOBULIN, POLOVOI GORMON-SVIAZYVAIUSHCHII GLOBULIN, ESTRADIOL-SVIAZYVAIUSHCHII GLOBULIN, TESTOSTERON-SVIAZYVAIUSHCHII GLOBULIN, ПОЛОВОЙ ГОРМОН-СВЯЗЫВАЮЩИЙ ГЛОБУЛИН, ТЕСТОСТЕРОН-СВЯЗЫВАЮЩИЙ ГЛОБУЛИН, ТЕСТОСТЕРОН-ЭСТРАДИОЛ-СВЯЗЫВАЮЩИЙ ГЛОБУЛИН, ЭСТРАДИОЛ-СВЯЗЫВАЮЩИЙ ГЛОБУЛИН |
| French |
Globuline fixant les hormones sexuelles, Globuline de transport des hormones sexuelles, SBP (Sex Steroid-Binding Protein), Globuline de fixation des hormones sexuelles, Globuline de liaison des hormones sexuelles, Globuline liant les hormones sexuelles, Globuline se liant aux hormones sexuelles, Protéine de transport des hormones sexuelles, Globuline de liaison aux hormones sexuelles, Protéine de liaison aux hormones stéroïdes sexuelles |
| Italian |
Globulina legante testosterone-estradiolo, Proteina legante ormoni sessuali steroidei, Globulina legante ormoni sessuali |
| Portuguese |
Globulina de Ligação a Testosterona e a Estradiol, Proteína de Ligação a Esteroide Sexual, Globulina Ligante de Testosterona e Estradiol, Globulina Ligante de Hormônio Sexual, Proteína Ligante de Esteroide Sexual, Globulina de Ligação a Hormônio Sexual |
| Polish |
Globuliny wiążące hormony płciowe
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| Japanese |
性ステロイド結合蛋白質, 性ホルモン結合グロブリン, テストステロンエストラジオール結合グロブリン, 性ホルモン結合性グロブリン |
| Spanish |
proteína fijadora de esteroides sexuales (sustancia), proteína fijadora de esteroides sexuales, Globulina de Unión a Estradiol Testosterona, Globulina de Unión a Hormona Sexual, Proteína de Unión a Esteroide Sexual |
| German |
Geschlechtshormonbindendes Globulin, Sexualhormonbindendes Globulin, Sexualsteroidbindendes Globulin, Testosteron-Estradiol-bindendes Globulin, Estradiol-bindendes Globulin, Globulin, Estradiol-bindendes, Globulin, Testosteron-bindendes, Testosteron-bindendes Globulin |
