Toxin Induced Skin Changes

Aka: Toxin Induced Skin Changes

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II. Causes: Diaphoretic Skin (Mnemonic: SOAP)

  1. Sympathomimetic Toxicity (contrast with Dry Skin with Anticholinergic Toxicity)
  2. Organophosphate Poisoning
  3. Aspirin (Salicylate Poisoning)
  4. Phencyclidine (PCP)

III. Causes: Needle Tracks

  1. Intravenous Cocaine
  2. Heroin
  3. Dapsone

IV. Causes: Red Skin

  1. Anticholinergic Toxicity
  2. Boric Acid
  3. Carbon Monoxide

V. Causes: Blue Skin

  1. See Skin Discoloration
  2. Cyanosis
  3. Methemoglobinemia
    1. Nitrates
    2. Nitrites
    3. Aniline dyes
    4. Phenazopyridine
  4. Chronic medication uses associated with blue-gray skin
    1. Amiodarone
    2. Argyria (Silver)
    3. Aresenic
    4. Alkaptonuria
    5. Gold Therapy

VI. Causes: Blistering

  1. Barbiturates
  2. Carbon Monoxide
  3. Sedative Hypnotics
  4. Snake Bites or Spider Bites
  5. Chemical Weapon (or Chemotherapy) exposure to Vesicants (Blister Agents)

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