II. Pathophysiology
- Agent
- Trichothecene Mycotoxins
- Produced by filamentous fungi (molds)
- Inactivation
- Extremely stable in heat and UV light
- Destruction requires heating 1500 F for 30 minutes
- Brief exposure to sodium Hypochlorite inactivates
- Trichothecene Mycotoxins
- Transmission
- Used as aerosolized Biological Weapon
- Laos, Kampuchea, Afghanistan in late 1970's
- Aerosol: "yellow rain" drops of yellow fluid
- Used as aerosolized Biological Weapon
III. Symptoms and signs
- Skin
- Respiratory
- Nose and throat pain
- Nasal Discharge
- Itching and sneezing
- Cough
- Dyspnea
- Wheezing
- Chest Pain
- Hemoptysis
- Severe systemic
IV. Differential Diagnosis
- Mustard agents
- Staphylococcal Enterotoxin B
- Ricin
V. Management
- Activated Charcoal for ingestion
VI. Prevention
- No Vaccine or antitoxin available
- Decontamination
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Related Studies
| Definition (CSP) | potent mycotoxin produced in feedstuffs by some Fusarium species. |
| Definition (MSH) | A potent mycotoxin produced in feedstuffs by several species of the genus FUSARIUM. It elicits a severe inflammatory reaction in animals and has teratogenic effects. |
| Concepts | Hazardous or Poisonous Substance (T131) , Organic Chemical (T109) |
| MSH | D013605 |
| SnomedCT | 39979007 |
| English | Fusariotoxin, Fusaritoxin, T 2 Toxin, T-2 Toxin, T2 Toxin, Toxin, T-2, Toxin, T2, Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 4,15-diacetate 8-(3-methylbutanoate), (3alpha,4beta,8alpha)-, T AA TOXIN 02, T-2 Toxin [Chemical/Ingredient], t 2 toxins, t-2 toxin, t2 mycotoxin, T-2 fungal toxin, T-2 toxin, T-2 fungal toxin (substance), T2 toxin, Mycotoxin T2 |
| French | Toxine T-2, Toxine T2, Fusariotoxine T-2, Mycotoxine T-2 |
| Swedish | T-2-toxin |
| Czech | T-2 toxin |
| Finnish | T-2-toksiini |
| Russian | FUZARITOKSIN, T-2 TOKSIN, T-2 ТОКСИН, ФУЗАРИТОКСИН |
| Italian | Tossina T2, Fusariotossina, Tossina T-2 |
| German | T AA TOXIN 02, Fusaritoxin, T-2-Toxin |
| Polish | Toksyna-2 |
| Japanese | フザリトキシン, T-2トキシン |
| Spanish | toxina T-2, toxina fúngica T-2 (sustancia), toxina fúngica T-2, micotoxina T-2 (sustancia), micotoxina T-2, Fusartoxina, Toxina T-2 |
| Portuguese | Fusaritoxina, Toxina T-2 |
Ontology: Trichothecenes (C0040952)
| Definition (MSH) | Usually 12,13-epoxytrichothecenes, produced by Fusaria, Stachybotrys, Trichoderma and other fungi, and some higher plants. They may contaminate food or feed grains, induce emesis and hemorrhage in lungs and brain, and damage bone marrow due to protein and DNA synthesis inhibition. |
| Concepts | Biologically Active Substance (T123) , Hazardous or Poisonous Substance (T131) , Organic Chemical (T109) |
| MSH | D014255 |
| SnomedCT | 693002 |
| LNC | LP64676-7 |
| English | Trichothecenes, Trichothecenes [Chemical/Ingredient], trichothecene, trichothecenes, Trichothecene, Fusarium toxins, Trichothecenes (substance), Fusarium toxins, NOS, Trichothecenes, NOS |
| Czech | trichotheceny |
| Finnish | Trikotekeenit |
| Russian | TRIKHOTETSENEPOKSIDY, TRIKHOTETSENY, EPOKSITRIKHOTETSENY, ТРИХОТЕЦЕНЫ, ТРИХОТЕЦЕНЭПОКСИДЫ, ЭПОКСИТРИХОТЕЦЕНЫ |
| Japanese | トリコテセンエポキシド, トリコテセン, エポキシトリコテセン |
| Swedish | Trikotecener |
| Polish | Trichoteceny |
| Spanish | toxina de fusario, tricotecenos (sustancia), tricotecenos, Tricotecenos |
| French | Trichothécènes |
| German | Trichothecene |
| Italian | Tricoteceni |
| Portuguese | Tricotecenos |
