II. Differential Diagnosis: Psychiatric Conditions
-
Schizophrenia
- Psychosis for >6 months, with an acute phase lasting one month or more
- Schizophreniform Disorder
- Psychosis Symptoms for >1 month and <6 months
- Consistent with Schizophrenia, but <6 months duration
- Schizoaffective disorder
- Psychosis with active phase symptoms for 1 month with concurrent Mood Disorder
- No Alcohol Dependence
-
Schizotypal Personality Disorder
- Persistent personality features that do not meet criteria for Schizophrenia and related conditions
-
Delusional disorder
- Non-bizarre Delusions without Hallucinations for 1 month
- No Alcohol Dependence
- Brief Psychotic Disorder
- Delusions, Hallucinations and Disorganized Speech or behavior for at least one day, but less than one month
- Shared Psychotic Disorder
- Folie a deux
-
Autism spectrum disorder (or communication disorders)
- Social interaction deficits with repetitive and restricted behaviors
-
Bipolar I Disorder
- Psychosis with manic phase
- Presents with 7 days or more of elevated or expansive mood, decreased sleep, goal directed activity
-
Major Depression
- Psychotic depression or drug resistant depression with Psychosis limited to times of Mood Disorder
- Postpartum Psychosis
- Brief Psychotic Disorder onset during pregnancy or within 4 weeks of delivery
-
Posttraumatic Stress Disorder
- Psychotic symptoms related to reaction to precipitating event
-
Obsessive Compulsive Disorder and Body Dysmorphic Disorder
- Significant Obsessions, compulsions or preoccupations related to body or associated repetitive behaviors
III. Differential Diagnosis: Organic Conditions (Secondary Psychosis)
-
Drug Induced Psychosis
- See Drug Induced Psychosis
- Medication toxicity
- Substance Abuse
- Medications and Antibiotics (Antibiomania)
- Electrolyte disturbance
- Endocrine and Metabolic disorders
- Hypoglycemia (or Hyperglycemia)
- Hypothyroidism or Hyperthyroidism
- Cushing Syndrome
- ACTH Producing Lung Cancer
- Hyperparathyroidism
- Acute intermittent porphyria
- Adult onset Tay-Sachs
- Wilson Disease
- Infectious disorders
- Sepsis
- HIV Infection
- Syphilis (neurosyphillis)
- Encephalitis
- Neurologic disorders
- Miscellaneous conditions
- Vitamin B1 Deficiency (Thiamine deficiency)
- Vitamin B3 Deficiency (Niacin Deficiency)
- Vitamin B12 Deficiency
- Systemic Lupus Erythematosus
- Porphyria
- ICU Psychosis
- Sleep Deprivation (e.g. Sleep Apnea)
- Malignancy
- Ovarian Teratoma
- Small Cell Lung Cancer
- Paraneoplastic limbic Encephalitis
IV. References
- (2013) DSM V, American Psychiatric Association, p. 99
- (2000) DSM IV, American Psychiatric Association, p. 297-343
- Freedman (2003) N Engl J Med 349:1738-49 [PubMed]
- Griswold (2015) Am Fam Physician 91(12):856-63 [PubMed]
- Holder (2014) Am Fam Physician 90(11): 775-82 [PubMed]
- Schultz (2007) Am Fam Physician 75:1821-9 [PubMed]
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Related Studies
| Concepts | Mental or Behavioral Dysfunction (T048) |
| ICD9 | 294 |
| English | Other organic psychotic conditions (chronic), Organic psychotic conditions (chronic), other, Other chronic organic psychotic conditions, Other organic psychotic conditions, Persistent mental disorders due to conditions classified elsewhere |
| Dutch | organische psychotische aandoeningen (chronisch), andere, andere organische psychotische aandoeningen (chronisch) |
| French | Autres troubles psychotiques organiques (chroniques), Autres conditions psychotiques organiques chroniques |
| German | organische psychotische Stoerungen (chronisch), organische psychotische Stoerungen (chronisch), sonstige |
| Italian | Altri stati (cronici) psicotici organici, Altri stati psicotici organici (cronici) |
| Portuguese | Situações (crónicas) de psicose orgânica, outras, Outras situações psicóticas orgânicas (crónicas) |
| Spanish | Otras enfermedades psicóticas orgánicas (crónicas) |
| Japanese | 器質精神病状態（慢性）、その他, ｷｼﾂｾｲｼﾝﾋﾞｮｳｼﾞｮｳﾀｲﾏﾝｾｲｿﾉﾀ |
| Czech | Jiné organické psychotické stavy (chronické), Organické psychotické stavy (chronické), jiné |
| Hungarian | Egyéb szervi psychotikus állapotok (chronikus), Organicus psychotikus állapotok (chronikus), egyéb |
Ontology: Psychotic disorder due to a general medical condition (C0748076)
| Definition (NCI) | A psychotic disorder characterized by prominent hallucinations or delusions that have been determined to be etiologically linked to a general medical condition. |
| Concepts | Mental or Behavioral Dysfunction (T048) |
| Italian | Disturbo psicotico dovuto a condizione medica sistemica, Disturbo psicotico dovuto a condizione medica sistemica NAS |
| Dutch | psychotische stoornis ten gevolge van een algemene medische conditie NAO, psychotische stoornis ten gevolge van een algemene medische conditie |
| French | Trouble psychotique dû à une affection médicale SAI, Trouble psychotique dû à une affection médicale |
| German | Psychose aufgrund einer Allgemeinerkrankung NNB, Psychose aufgrund einer Allgemeinerkrankung |
| Portuguese | Perturbação psicótica devida a quadro do foro médico NE, Perturbação psicótica devida a quadro do foro médico |
| Spanish | Trastorno psicótico por causa de condición médica general NEOM, Trastorno psicótico por causa de condición médica general |
| Japanese | 身体疾患による精神病性障害ＮＯＳ, 身体疾患による精神病性障害, ｼﾝﾀｲｼｯｶﾝﾆﾖﾙｾｲｼﾝﾋﾞｮｳｾｲｼｮｳｶﾞｲ, ｼﾝﾀｲｼｯｶﾝﾆﾖﾙｾｲｼﾝﾋﾞｮｳｾｲｼｮｳｶﾞｲNOS |
| English | psychotic disorder due to general medical condition, psychotic disorder due to general medical condition (diagnosis), Psychotic disorder due to a general medical condition NOS, Psychotic Disorder Due to a General Medical Condition, Psychotic disorder due to a general medical condition |
| Czech | Psychotická porucha způsobená celkovým zdravotním stavem, Psychotická porucha způsobená celkovým zdravotním stavem NOS |
| Hungarian | Általános egészségi állapot okozta psychotikus betegség k.m.n., Általános betegséghez társuló psychotikus zavar |
