Mania Secondary Causes

Aka: Mania Secondary Causes, Secondary Mania

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II. General

  1. Consider secondary causes if outside typical ages
    1. Onset in pre-pubertal children
    2. Onset after age 40 years

III. Causes: Drugs of Abuse

  1. Alcohol Abuse
  2. Amphetamine abuse
  3. Cocaine Abuse
  4. Hallucinogen abuse
  5. Opiate Abuse
  6. Bath Salts
  7. Phencyclidine (PCP)

IV. Causes: Collagen vascular disease

  1. Systemic Lupus Erythematosus

V. Causes: Infectious disease

  1. Neurosyphilis
  2. HSV Encephalitis
  3. Influenza
  4. Encephalitis (e.g. Arboviruses such as St. Louis Encephalitis)
  5. HIV Encephalitis

VI. Causes: Endocrine disease

  1. Hyperthyroidism
  2. Hypothyroidism
  3. Cushing Disease

VII. Causes: Neurologic disease

  1. Multiple Sclerosis
  2. Huntington's Chorea
  3. Wilson Disease
  4. Head Trauma
  5. Complex Partial Seizures
  6. Cerebrovascular Accidents
  7. Migraine Headache
  8. Neoplasms (esp. diencephalic or Third Ventricle)

VIII. Causes: Vitamin Deficiency

  1. Vitamin B12 Deficiency
  2. Folate Deficiency
  3. Niacin Deficiency
  4. Thiamine deficiency

IX. Causes: Medications

  1. Neuropsychiatric
    1. Monoamine Oxidase Inhibitors
    2. Heterocyclic Antidepressants
    3. Methylphenidate (Ritalin)
    4. Disulfiram (Antabuse)
    5. Levodopa
    6. Levetiracetam (Keppra)
  2. Cardiovascular
    1. Captopril
    2. Hydralazine
  3. Endocrine
    1. Bromocriptine
    2. Corticosteroids
  4. Miscellaneous
    1. Baclofen
    2. Bromide
    3. Procarbazine
    4. Yohimbine
    5. Cimetidine
    6. Isoniazid
    7. HIV Medications (including Integrase Inhibitors)

X. References

  1. Marzani (2021) Am Fam Physician 103(4): 227-39 [PubMed]
  2. Price (2012) Am Fam Physician 85(5): 483-93 [PubMed]
  3. Werder (1995) Am Fam Physician 51(5):1126-36 [PubMed]

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Related Studies

Ontology: Manic (C0338831)

Definition (NCI) Excitement of psychotic proportions manifested by mental and physical hyperactivity, disorganisation of behaviour and elevation of mood.(On-line Medical Dictionary)
Definition (NCI_CTCAE) A disorder characterized by excitement of psychotic proportions manifested by mental and physical hyperactivity, disorganization of behavior and elevation of mood.
Concepts Mental or Behavioral Dysfunction (T048)
MSH D001714
ICD10 F30.9
SnomedCT 154872008, 268750008, 231494001
English Manias, Manic State, Manic States, State, Manic, States, Manic, MANIA, Manic, Manic state, Mania NOS, manic state, manic, Mania (disorder), mania, Mania
French MANIE, Etat maniaque, Manie, État maniaque
Portuguese MANIA, Estado maníaco, Mania
Spanish MANIA, Estado maníaco, manía (trastorno), maníaco, manía, Manía
Dutch manische toestand, manie
German manischer Zustand, MANIE, Manie
Japanese ｿｳﾋﾞｮｳ, ｿｳｼﾞｮｳﾀｲ, 躁障害, 躁状態, 躁病, そう病, 躁狂, そう状態, 定型的躁状態, メーニア
Czech mánie, Manický stav, Mánie
Italian Mania, Stato maniacale
Hungarian Mania, Maniás állapot
Norwegian Mani
Derived from the NIH UMLS (Unified Medical Language System)

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