II. Epidemiology
- Endemic Hepatitis B
- Mediterranean basin
- South America
- Percutaneous spread via Intravenous Drug Abuse
- Transfusion (e.g. Hemophilia)
III. Pathophysiology
- Defective 37 nm RNA virus
- Requires Hepatitis BVirus for replication
- Enhances severity of Hepatitis B infection
- Transmission
- Coinfection with Hepatitis B
- Superinfection of a Hepatitis B Carrier
IV. Differential Diagnosis
V. Labs
- Hepatitis D Serology (xHDV)
- Higher titers suggest chronic Hepatitis D
VI. Management
VII. Complications
- Fulminant Hepatitis
- Chronic Hepatitis
- Cirrhosis
VIII. Prevention
- Hepatitis B Vaccine for Non-Carriers of Hepatitis B