Reye's Syndrome

Aka: Reye's Syndrome, Reye Syndrome

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II. Pathophysiology

  1. Hepatic Encephalopathy in children under age 14

III. Associated Conditions

  1. Influenza B
  2. Varicella Zoster Virus
  3. Salicylate (Aspirin) use

IV. Symptoms and Signs

  1. Nausea or Vomiting
  2. Neurologic
    1. Lethargy
    2. Delirium
    3. Seizures

V. Labs

  1. Liver Function Tests increased
    1. Aspartate Aminotransferase (AST) increased
    2. Alanine Aminotransferase (ALT) increased
    3. Ammonia increased
  2. Cerebrospinal Fluid (CSF) Normal

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