Definition (CHV)
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steroid drug being studied as a cancer preventive drug
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Definition (CHV)
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steroid drug being studied as a cancer preventive drug
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Definition (CHV)
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steroid drug being studied as a cancer preventive drug
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Definition (CHV)
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steroid drug being studied as a cancer preventive drug
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Definition (CHV)
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steroid drug being studied as a cancer preventive drug
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Definition (CHV)
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steroid drug being studied as a cancer preventive drug
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Definition (NCI_NCI-GLOSS)
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A substance being studied in the prevention of cancer. It is a type of steroid.
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Definition (NCI)
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A synthetic form of dehydroepiandrosterone with potential chemopreventive activity. Produced endogenously, dehydroepiandrosterone (DHEA) is an intermediate in the conversion of cholesterol to androgens and estrogens. Although the mechanisms of action of exogenously administered DHEA have not been fully illuminated, they may result in both direct and indirect physiologic effects. Direct effects include GABA-a receptor complex and NMDA receptor modulation, and enhanced pancreatic beta cell insulin secretion and antiglucocorticoid activities. (NCI04)
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Definition (MSH)
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A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
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Definition (CSP)
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major C19 steroid produced by the adrenal cortex; also produced in small quantities in the testis and the ovary; dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione; estradiol; and estrone; most of DHEA is sulfated (dehydroepiandrosterone sulfate) before secretion.
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Definition (PDQ)
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A synthetic form of dehydroepiandrosterone with potential chemopreventive activity. Produced endogenously, dehydroepiandrosterone (DHEA) is an intermediate in the conversion of cholesterol to androgens and estrogens. Although the mechanisms of action of exogenously administered DHEA have not been fully illuminated, they may result in both direct and indirect physiologic effects. Direct effects include GABA-a receptor complex and NMDA receptor modulation, and enhanced pancreatic beta cell insulin secretion and antiglucocorticoid activities. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42419&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42419&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2265" NCI Thesaurus)
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Concepts |
Hormone
(T125)
, Steroid
(T110)
, Pharmacologic Substance
(T121)
|
MSH |
D003687
|
SnomedCT |
103052000, 78316004, 413963008 |
LNC |
LP15528-0, MTHU003476 |
English |
Androstenolone, Dehydroisoandrosterone, DHEA, Androst-5-en-17-one, 3-hydroxy-, (3beta)-, 3beta-Hydroxyandrost-5-en-17-one, Therapeutic Dehydroepiandrosterone, androstenolone, prasterone (medication), 17-Hormoforin, 5,6-Dehydroisoandrosterone, Dehydroepiandrosterone [Chemical/Ingredient], dehydroisoandrosterone, dheas, dhea, dehydroepiandrosterone (DHEA), prasterone (DHEA), PRASTERONE, prasterone, Androstenolone (substance), Dehydroepiandrosterone, Prasterone, 5 Androsten 3 beta hydroxy 17 one, 5-Androsten-3-beta-hydroxy-17-one, DHA - Dehydroepiandrosterone, DHEA - Dehydroepiandrosterone, Dehydro-3-epiandrosterone, Dehydroepiandrosterone (substance), Androstenolone -RETIRED-, DHEA preparation, DHEA product, Dehydroepiandrosterone preparation (product), Dehydroepiandrosterone preparation, dehydroepiandrosterone, DEHYDROEPIANDROSTERONE |
Swedish |
Dehydroepiandrosteron
|
Czech |
dehydroepiandrosteron, dehydroisoandrosteron, prasteron |
Finnish |
Dehydroepiandrosteroni
|
French |
Prastérone, 3bêta-Hydroxy-androst-5-én-17-one, 3bêta-Hydroxyandrost-5-én-17-one, Déhydroépiandrostérone, Déhydroisoandrostérone, DHEA |
Russian |
DEGIDROEPIANDROSTERON, DEGIDROIZOANDROSTERON, PRASTERON, ДЕГИДРОИЗОАНДРОСТЕРОН, ДЕГИДРОЭПИАНДРОСТЕРОН, ПРАСТЕРОН |
Spanish |
preparado con dihidroepiandrosterona (producto), dihidroepiandrosterona (producto), dihidroepiandrosterona, preparado con dihidroepiandrosterona, androstenolona - RETIRADO -, dehidro - 3 - epiandrosterona, androstenolona - RETIRADO - (concepto no activo), dehidroepiandrosterona (sustancia), dehidroepiandrosterona, Deshidroepiandrosterona, Deshidroisoandrosterona, Prasterona |
Italian |
5-Androstene-3-beta-idrossi-17-one, Prasterone, Androstenolone, DHEA, Deidroisoandrosterone, Diidroepiandrosterone |
Polish |
Dehydroizoandrosteron, Dehydroepiandrosteron, Prasteron, DHEA |
Japanese |
アンドロステノロン, trans-デヒドロアンドロステロン, デヒドロイソアンドロステロン, デヒドロエピアンドロステロン, プラステロン |
Croatian |
DHEA, DEHIDROEPIANDROSTERON |
Norwegian |
Dehydroepiandrosteron, Androstenolon, DHEA, 5-androsten-3-betahydroksi-17-on, Dehydroisoandrosteron |
Portuguese |
DHEA, Desidroepiandrosterona, Desidroisoandrosterona, Prasterona |
German |
Dehydroepiandrosteron, Dehydroisoandrosteron, Prasteron |