II. Techniques
- Blood Doping (Blood Boosting)
- Recombinent Erythropoietin (rEPO)
- Stimulates red cell mass
- Very expensive
- Same effect as Blood Doping
III. Adverse Effects
- Hypercoagulation risk may be fatal
- Deep Vein Thrombosis
- Pulmonary Embolism
- Cerebrovascular Accident
- Myocardial Infarction
- Eighteen deaths by European Cyclists who blood doped
- Transfusion Reaction
- Bloodbourne infection (including HIV)
IV. Efficacy
- Increases performance in endurance sports (e.g. long-distance cycling)
V. Detection
- Not detected, but banned by olympic committee 1984
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Definition (NCI) | A recombinant therapeutic agent which is chemically identical to or similar to the endogenous glycoprotein erythropoietin (Epo). Epo promotes the differentiation and maturation of hematopoietic progenitors into erythrocytes; is a mitogen and a chemoattractant for endothelial cells; stimulates activated and differentiated B-cells and enhances B-cell immunoglobulin production and proliferation; and is hypoxia-inducible. (NCI04) |
Concepts | Pharmacologic Substance (T121) , Amino Acid, Peptide, or Protein (T116) |
MSH | D019321 |
Swedish | Erytropoietin, rekombinant |
Finnish | Yhdistelmä-erytropoietiini |
Japanese | エリスロポエチン-組換え, 組換えエリトロポイエチン, 組換えエリスロポエチン |
English | erythropoietin recombinant, recombinant erythropoietin, ERYTHROPOIETIN, r-HuEPO, Erythropoietin, Erythrocyte Colony Stimulating Factor, Hematopoietin, Recombinant EPO, Recombinant Erythropoietin |